Department of Genetics, University of Alberta, Edmonton, Alberta, Canada T6G 2E9.
Genetics. 1980 Mar;94(3):777-89. doi: 10.1093/genetics/94.3.777.
The linkage disequilibrium expected in a finite, partially selfing population is analyzed, assuming the infinite allele model. Formulas for the expected sum of squares of the linkage disequilibria and the squared standard linkage disequilibrium are derived from the equilibrium values of sixteen inbreeding coefficients required to describe the behavior of the system. These formulas are identical to those obtained with random mating if the effective population size N(e) = (1-(1/2)S)N and the effective recombination value r(e) = (1-S)r/(1-(1/2)S), where S is the proportion of selfing, are substituted for the population size and the recombination value. Therefore, the effect of partial selfing at equilibrium is to reduce the population size by a factor 1-(1/2)S and the recombination value by a factor (1-S)/(1-(1/2)S).
在有限的部分自交群体中，分析了连锁不平衡的预期情况，假设无限等位基因模型。从描述系统行为所需的十六个近交系数的平衡值中推导出连锁不平衡和平方标准连锁不平衡的预期平方和的公式。如果将有效群体大小 N(e) = (1-(1/2)S)N 和有效重组值 r(e) = (1-S)r/(1-(1/2)S)代入群体大小和重组值，这些公式与随机交配时获得的公式相同，其中 S 是自交的比例。因此，平衡时部分自交的影响是将群体大小减少 1-(1/2)S 的因子，将重组值减少(1-S)/(1-(1/2)S)的因子。
