Department of Mathematics, Stanford University, Stanford, California 94305.
Genetics. 1981 Feb;97(2):457-73. doi: 10.1093/genetics/97.2.457.
The maintenance of genetic polymorphism under various natural structured viability regimes vs. general unrestricted fitness assignments are compared. The selection models considered include a generalized dominance fitness system, a generalized viability model based on allelic activity values, viability matrices based on multilocus activity levels, viability matrices defined by partitioned "resource" or "substrate" variables, and circulant-type viability matrices. A number of examples that support these formulations are discussed. Detailed results on the nature of the genotype frequency equilibrium configurations for the specified viability models are presented. An increased likelihood for a globally stable equilibrium is predicted for the more structured viability models.
在各种自然结构生存能力制度与普遍不受限制的适应力分配下，遗传多态性的维持情况进行了比较。所考虑的选择模型包括广义优势适应力系统、基于等位基因活性值的广义生存力模型、基于多位点活性水平的生存力矩阵、基于划分的“资源”或“基质”变量的生存力矩阵以及循环型生存力矩阵。讨论了一些支持这些公式的例子。针对指定生存力模型，给出了基因型频率平衡配置的详细结果。预测更具结构性的生存力模型会增加全局稳定平衡的可能性。
