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基于方差分量分析的遗传力最小方差估计的一种逼近。

An approximation of the minimum-variance estimator of heritability based on variance component analysis.

机构信息

Departments of Dairy Science and Animal Science, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.

出版信息

Genetics. 1981 Jun;98(2):417-26. doi: 10.1093/genetics/98.2.417.

DOI:10.1093/genetics/98.2.417
PMID:17249092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1214450/
Abstract

An approximate minimum-variance estimate of heritability (h(2)) is proposed, using the sire and dam components of variance from a hierarchical analysis of variance. The minimum sampling variance is derived for unbalanced data. Optimum structures for the estimation of h(2) are given for the balanced case. The degree to which ĥ(2) is more precise than the equally weighted estimate ĥ(2) (S+D) is a function of the size and structure of the sample used. However, computer simulation reveals that ĥ(2) has less desirable behavior than ĥ(2) (S+D). An iterative procedure improved the estimation of h(2), especially in small populations, when those values of ĥ(2) (S) or ĥ(2) (D) outside the range of the parameter were constrained to zero or unity.

摘要

提出了一种使用方差的父本和母本分量的遗传力(h(2))的近似最小方差估计,该方法来自方差的层次分析。为不平衡数据推导出最小抽样方差。对于平衡情况,给出了 h(2)的最佳估计结构。ĥ(2)比等权重估计ĥ(2)(S+D)更精确的程度取决于所用样本的大小和结构。然而,计算机模拟表明,ĥ(2)的行为不如ĥ(2)(S+D)理想。迭代过程改进了 h(2)的估计,尤其是在小种群中,当那些超出参数范围的ĥ(2)(S)或ĥ(2)(D)值被约束为零或一。

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On a method of estimating the genetic correlation between characters measured in different experimental units.一种估计在不同实验单位中测量的性状间遗传相关的方法。
Theor Appl Genet. 1984 Jan;67(2-3):175-8. doi: 10.1007/BF00317027.
2
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本文引用的文献

1
Probability of obtaining negative estimates of heritability.获得遗传力负估计值的概率。
Biometrics. 1968 Sep;24(3):517-26.
2
Estimation of heritability by both regression of offspring on parent and intra-class correlation of sibs in one experiment.在一项实验中,通过子代对亲代的回归分析和同胞间的组内相关分析来估计遗传力。
Biometrics. 1974 Sep;30(3):447-68.