Nam Ji Hyung, Kim Seung Min, Choi Jae Hyeuk, Lee Yong Kuk, Baek Jin Ho, Jang Tae Jung, Park Keon Uk
Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, Kora.
Korean J Intern Med. 2006 Dec;21(4):248-51. doi: 10.3904/kjim.2006.21.4.248.
Malignant melanoma of the lacrimal sac is very rare and primary malignant melanoma is extremely rare. It is usually diagnosed at an advanced stage after excision or biopsy of a tumor. We treated a patient with tearing and bloody discharge from the left eye. We performed a dacryocystectomy with the suspicion of a chronic dacryocystitis. However, the pathological findings and the immunohistochemical studies showed a malignant melanoma of the lacrimal sac. The patient underwent postoperative irradiation therapy. Follow up two months after surgery revealed no evidence of recurrence. Early diagnosis is very important for prognosis in patients with malignant melanoma of the lacrimal sac. Because this tumor often presents with symptoms similar to dacryocystitis and may masquerade as a chronic dacryocystitis, it can be difficult to make an early diagnosis.
泪囊恶性黑色素瘤非常罕见,原发性恶性黑色素瘤极为罕见。它通常在肿瘤切除或活检后处于晚期时才被诊断出来。我们治疗了一名左眼流泪和血性分泌物的患者。我们怀疑是慢性泪囊炎而进行了泪囊切除术。然而,病理检查结果和免疫组化研究显示为泪囊恶性黑色素瘤。该患者接受了术后放射治疗。术后两个月的随访未发现复发迹象。早期诊断对泪囊恶性黑色素瘤患者的预后非常重要。由于这种肿瘤常表现出与泪囊炎相似的症状,可能伪装成慢性泪囊炎,因此很难做出早期诊断。