Li Yang-Jun, Zhu Shao-Jun, Yan Hong, Han Jing, Wang Dan, Xu Shuang
Department of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University of PLA, Xian, People's Republic of China.
BMJ Case Rep. 2012 Aug 13;2012:bcr2012006349. doi: 10.1136/bcr-2012-006349.
Primary malignant melanoma of the lacrimal sac is extremely rare. It is usually diagnosed at an advanced stage after excision or biopsy of a tumour. We treated a 59-year-old man with tearing and bloody discharge from the right eye. Clinical examination revealed a firm, localised mass at the inner canthus consistent with a lacrimal sac swelling. Sac washout demonstrated obstruction to entry into the lacrimal sac with a reflux of blood-stained fluid. The pathological findings and the immunohistochemical studies showed a malignant melanoma of the lacrimal sac. We performed radical surgery and radiation therapy. Follow-up 4 months after surgery revealed no evidence of recurrence. Because this tumour often presents with symptoms similar to dacryocystitis and may masquerade as a chronic dacryocystitis, ophthalmologists should be aware of this disease entity when encountered with patients with epiphora and mass in the medial canthal area.
泪囊原发性恶性黑色素瘤极为罕见。通常在肿瘤切除或活检后晚期才得以诊断。我们治疗了一名59岁男性,其右眼有流泪和血性分泌物。临床检查发现内眦处有一个质地坚硬的局限性肿块,与泪囊肿胀相符。泪囊冲洗显示进入泪囊受阻,伴有血性液体反流。病理检查结果和免疫组化研究显示为泪囊恶性黑色素瘤。我们进行了根治性手术和放射治疗。术后4个月的随访未发现复发迹象。由于这种肿瘤常表现出与泪囊炎相似的症状,可能伪装成慢性泪囊炎,眼科医生在遇到内眦部溢泪和肿块的患者时应意识到这种疾病。