基于流体原核染色体模型的线粒体起源
The origin of mitochondria in light of a fluid prokaryotic chromosome model.
作者信息
Esser Christian, Martin William, Dagan Tal
机构信息
Institut für Botanik III, Heinrich-Heine Universität Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf, Germany.
出版信息
Biol Lett. 2007 Apr 22;3(2):180-4. doi: 10.1098/rsbl.2006.0582.
Biologists agree that the ancestor of mitochondria was an alpha-proteobacterium. But there is no consensus as to what constitutes an alpha-proteobacterial gene. Is it a gene found in all or several alpha-proteobacteria, or in only one? Here, we examine the proportion of alpha-proteobacterial genes in alpha-proteobacterial genomes by means of sequence comparisons. We find that each alpha-proteobacterium harbours a particular collection of genes and that, depending upon the lineage examined, between 97 and 33% are alpha-proteobacterial by the nearest-neighbour criterion. Our findings bear upon attempts to reconstruct the mitochondrial ancestor and upon inferences concerning the collection of genes that the mitochondrial ancestor possessed at the time that it became an endosymbiont.
生物学家们一致认为，线粒体的祖先是一种α-变形菌。但对于什么构成α-变形菌基因，尚无定论。是在所有或几种α-变形菌中发现的基因，还是仅在一种α-变形菌中发现的基因呢？在这里，我们通过序列比较来研究α-变形菌基因组中α-变形菌基因的比例。我们发现，每种α-变形菌都拥有一组特定的基因，并且根据所研究的谱系不同，按照最近邻标准，97%至33%的基因是α-变形菌基因。我们的研究结果与重建线粒体祖先的尝试以及关于线粒体祖先成为内共生体时所拥有的基因集合的推断有关。
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