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一名多发性骨髓瘤患者的显著角膜神经。

Prominent corneal nerves in a patient with multiple myeloma.

作者信息

Parghi Chirag, McKnight G Tipton, Pflugfelder Stephen C

机构信息

Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Cornea. 2007 Feb;26(2):220-2. doi: 10.1097/01.ico.0000231492.89539.eb.

DOI:10.1097/01.ico.0000231492.89539.eb
PMID:17251817
Abstract

PURPOSE

To describe a case of prominent corneal nerves observed in a patient after diagnosis of multiple myeloma.

METHODS

Case report and literature review.

RESULTS

A 65-year-old woman with a history of multiple myeloma was referred for chronic epitheliopathy in the left eye. She was diagnosed with multiple myeloma 3 years before presentation and underwent treatment at that time. On examination, she was noted to have prominent corneal nerves bilaterally with absent corneal sensation.

CONCLUSION

Multiple myeloma caused prominent corneal nerves and reduced corneal sensitivity.

摘要

目的

描述一例在诊断为多发性骨髓瘤后患者出现角膜神经突出的病例。

方法

病例报告及文献综述。

结果

一名有多发性骨髓瘤病史的65岁女性因左眼慢性上皮病变前来就诊。她在就诊前3年被诊断为多发性骨髓瘤并接受了治疗。检查发现,她双侧角膜神经突出,角膜感觉缺失。

结论

多发性骨髓瘤导致角膜神经突出并降低角膜敏感性。

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Prominent corneal nerves in a patient with multiple myeloma.一名多发性骨髓瘤患者的显著角膜神经。
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引用本文的文献

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Exploring the ocular involvement in multiple myeloma: a comprehensive review of 70-year clinical studies.探索多发性骨髓瘤的眼部受累:70年临床研究的综合综述
Int Ophthalmol. 2025 Mar 14;45(1):89. doi: 10.1007/s10792-025-03467-9.
2
Corneal Opacity Leading to Multiple Myeloma Diagnosis: A Case Report and Literature Review.角膜混浊导致多发性骨髓瘤诊断:一例报告及文献综述
Am J Case Rep. 2018 Apr 10;19:421-425. doi: 10.12659/ajcr.908475.
3
Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report.
共聚焦角膜显微镜检查发现多发性骨髓瘤所致轻链型淀粉样变性神经病患者的角膜神经纤维受累:一例报告
Case Rep Neurol. 2016 Jun 27;8(2):134-9. doi: 10.1159/000446538. eCollection 2016 May-Aug.
4
Cloudy corneas as an initial presentation of multiple myeloma.角膜混浊作为多发性骨髓瘤的初始表现。
Clin Ophthalmol. 2014 Apr 28;8:813-7. doi: 10.2147/OPTH.S49283. eCollection 2014.
5
Ophthalmic manifestations of atypical IgD multiple myeloma.非典型IgD型多发性骨髓瘤的眼部表现
BMJ Case Rep. 2012 Jul 19;2012:bcr2012006486. doi: 10.1136/bcr-2012-006486.