Akamatsu Shusuke, Kinoshita Hidefumi, Shimizu Yosuke, Yoshimura Koji, Ito Noriyuki, Kamoto Toshiyuki, Ogawa Osamu
Department of Urology, Kyoto University Graduate School of Medicine.
Hinyokika Kiyo. 2006 Dec;52(12):947-50.
Patients with autosomal dominant polycystic kidney disease (ADPKD) often suffer from abdominal symptoms. Although laparoscopic nephrectomy has been reported as a minimally invasive therapy, it is still technically demanding due to the large size of the kidneys. Transarterial embolization (TAE) is one of the alternatives, but there are only limited reports on its application in ADPKD. We describe a case in which bilateral nephrectomy was performed as a second-line treatment after TAE. One kidney was removed because a small feeding arterial branch was not completely embolized. The other kidney was removed due to infection. Retroperitoneoscopic nephrectomy was a good choice as a second-line modality in the case without infection because the volume of the kidney was reduced even with incomplete TAE, and adhesion after TAE was minimal. TAE is an effective choice in ADPKD patients without infection as a first-line treatment even when complete embolization is difficult, since nephrectomy after TAE is technically easier than removal of a fresh ADPKD kidney.
常染色体显性多囊肾病(ADPKD)患者常出现腹部症状。尽管腹腔镜肾切除术已被报道为一种微创治疗方法,但由于肾脏体积较大,其技术要求仍然很高。经动脉栓塞术(TAE)是一种替代方法,但关于其在ADPKD中的应用报道有限。我们描述了一例在TAE后进行双侧肾切除术作为二线治疗的病例。其中一个肾脏被切除是因为一条小的供血动脉分支未完全栓塞。另一个肾脏因感染而被切除。在没有感染的情况下,后腹腔镜肾切除术作为二线治疗方式是一个不错的选择,因为即使TAE不完全,肾脏体积也会减小,且TAE后的粘连极少。对于没有感染的ADPKD患者,即使完全栓塞困难,TAE作为一线治疗也是一种有效的选择,因为TAE后的肾切除术在技术上比切除新鲜的ADPKD肾脏更容易。