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[憩室病病理生理学的当前概念]

[Current concepts of diverticular disease pathophysiology].

作者信息

Frey Janusz, Gil Krzysztof, Wałega Piotr, Herman Roman Maria

机构信息

III Katedra i Klinika Chirurgii Ogólnej, Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.

出版信息

Folia Med Cracov. 2005;46(3-4):125-35.

PMID:17252995
Abstract

The first description of diverticular disease (DD) is dated on XVIIIth century. During last decades the DD prevalence continuously increases, especially in western countries. Nowadays, in developed countries, DD of the left colon is one of the most common diseases of gastro-intestinal tract. Because of the prevalence and costs of treatment it is still in the limelight of scientists and medical professionals. This article summarizes basic epidemiological data and discusses actual concepts of DD pathophysiology. Despite fact DD becomes more and more important, its pathophysiology remains to be unrevealed yet. Further clinical, molecular and epidemiological studies are needed to show the process and particular stages of diverticula development and progression.

摘要

憩室病(DD)的首次描述可追溯到18世纪。在过去几十年中,DD的患病率持续上升,尤其是在西方国家。如今,在发达国家,左半结肠憩室病是胃肠道最常见的疾病之一。由于其患病率和治疗成本,它仍然是科学家和医学专业人员关注的焦点。本文总结了基本的流行病学数据,并讨论了DD病理生理学的实际概念。尽管DD变得越来越重要,但其病理生理学仍有待揭示。需要进一步的临床、分子和流行病学研究来阐明憩室发展和进展的过程及特定阶段。

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