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脊柱间叶性肿瘤的外科治疗

Surgical management of spinal mesenchymal tumors.

作者信息

Mody Milan G, Rao Ganesh, Rhines Laurence D

机构信息

Department of Neurosurgery, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

出版信息

Curr Oncol Rep. 2006 Jul;8(4):297-304. doi: 10.1007/s11912-006-0036-2.

Abstract

Primary and metastatic spinal mesenchymal tumors are uncommon lesions. Surgical management of these tumors remains a challenge. En bloc wide resection provides the best chance for local tumor control and long-term survival. However, limitations to this technique include technical considerations (including neurovascular anatomy), patient selection, and tumor histology. Intralesional resection provides good neurologic outcomes, but local recurrence rates are high. Postoperative adjuvant chemotherapy with or without radiation may help to delay recurrence and improve outcomes. We present three cases of our surgical experience with spinal mesenchymal tumors for illustrative purposes.

摘要

原发性和转移性脊柱间叶性肿瘤是罕见的病变。这些肿瘤的外科治疗仍然是一项挑战。整块广泛切除为局部肿瘤控制和长期生存提供了最佳机会。然而,该技术的局限性包括技术因素(包括神经血管解剖结构)、患者选择和肿瘤组织学。病灶内切除可取得良好的神经学结果,但局部复发率较高。术后辅助化疗(无论是否联合放疗)可能有助于延缓复发并改善预后。为了说明情况,我们介绍三例脊柱间叶性肿瘤的手术经验。

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