慢性淋巴细胞白血病B淋巴细胞细胞膜的特征。I. II类抗原（HLA-D）的表达
[Characteristics of cell membrane of B-lymphocytes in chronic lymphocytic leukemia. I. Expression of class II antigens (HLA-D)].
作者信息
Pluta A, Górski A, Nowaczyk M
机构信息
Kliniki Hematologii A. M. w Lublinie.
出版信息
Pol Arch Med Wewn. 1991 Sep;86(3):149-53.
PMID:1725558
Abstract
Surface expression of class II antigens (HLA-D) on B lymphocytes was studied in 47 patients with chronic lymphatic leukemia (CLL) with an aid of monoclonal antibodies against monomorphic determinants of DR, DP and DQ. An association was found between progression of disease and gradual loss of those markers, especially DP and DQ.
摘要
借助针对DR、DP和DQ单态决定簇的单克隆抗体，对47例慢性淋巴细胞白血病（CLL）患者B淋巴细胞上II类抗原（HLA-D）的表面表达进行了研究。发现疾病进展与这些标志物尤其是DP和DQ的逐渐丧失之间存在关联。
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