Chahwan Santiago, Miller M Todd, Pigott John P, Whalen Ralph C, Jones Linda, Comerota Anthony J
Jobst Vascular Center, Toledo, Ohio 43606, USA.
J Vasc Surg. 2007 Mar;45(3):523-6. doi: 10.1016/j.jvs.2006.11.044. Epub 2007 Jan 25.
Correlation of carotid duplex ultrasound (DUS) flow velocities with carotid artery stenosis before and after carotid endarterectomy is well established. With the evolution of catheter-based techniques, carotid stenosis increasingly is being treated with angioplasty and stenting (CAS). CAS changes the physical properties of the arterial wall, which may alter blood flow velocities compared with the nonstented carotid. Opinions differ about whether DUS is a reliable tool to assess technical outcome and recurrent stenosis after CAS. This study correlated carotid DUS flow velocity findings with carotid arteriography after CAS.
Data from 77 pairs of carotid arteriograms with corresponding DUS after CAS in 68 patients were reviewed. Preintervention and postintervention DUS and carotid arteriogram data were evaluated for each patient. Peak systolic velocities (PSV), end-diastolic velocities (EDV), and internal carotid artery/common carotid artery ratios (ICA/CCA) were correlated with the post-CAS arteriogram.
The mean preintervention PSV was 390 +/- 110 cm/s (range, 216 to 691 cm/s), and the average EDV was 134 +/- 51 cm/s (range, 35 to 314 cm/s). Postintervention DUS was obtained a mean of 5 days after CAS (range, 1 to 30 days). Sixty (81%) post-CAS arteriograms were normal, and each corresponded to a normal postintervention DUS (PSV range, 30 to 118 cm/s; EDV range, 18 to 60 cm/s). In 14 arteries (19%), completion arteriograms revealed residual stenoses of 20% to 40% in 13, and 50% in one. The mean PSV was 175 cm/s (range, 137 to 195 cm/s), and the mean EDV was 44 cm/s (range, 20 to 62 cm/s). All velocities exceeded the threshold of a 50% stenosis by DUS criteria for a nonstented carotid artery. In three arteries (2 patients), high-grade recurrent stenoses detected by DUS developed that required reintervention during follow-up. This high-grade restenosis was confirmed by arteriography in each patient, providing an additional three correlations.
Normal DUS imaging reliably identifies arteriographically normal carotid arteries after CAS. Carotid velocities are disproportionately elevated with mild and moderate degrees of stenoses, and velocity criteria for quantitating stenoses in these patients require modification. However, DUS appropriately identifies severe recurrent stenoses after CAS.
颈动脉内膜剥脱术前、后颈动脉双功超声(DUS)血流速度与颈动脉狭窄的相关性已得到充分证实。随着基于导管技术的发展,越来越多的颈动脉狭窄采用血管成形术和支架置入术(CAS)进行治疗。CAS改变了动脉壁的物理特性,与未置入支架的颈动脉相比,这可能会改变血流速度。对于DUS是否是评估CAS术后技术效果和再狭窄的可靠工具,存在不同观点。本研究将CAS术后颈动脉DUS血流速度结果与颈动脉血管造影结果进行了相关性分析。
回顾了68例患者77对CAS术后相应DUS的颈动脉血管造影数据。对每位患者的干预前和干预后DUS及颈动脉血管造影数据进行评估。将收缩期峰值速度(PSV)、舒张末期速度(EDV)和颈内动脉/颈总动脉比值(ICA/CCA)与CAS术后血管造影结果进行相关性分析。
干预前平均PSV为390±110 cm/s(范围216至691 cm/s),平均EDV为134±51 cm/s(范围35至314 cm/s)。干预后DUS平均在CAS术后5天(范围1至30天)获得。60例(81%)CAS术后血管造影正常,且每例均对应干预后正常的DUS(PSV范围30至118 cm/s;EDV范围18至60 cm/s)。14条动脉(19%)中,完成血管造影显示13条存在20%至40%的残余狭窄,1条存在50%的残余狭窄。平均PSV为175 cm/s(范围137至195 cm/s),平均EDV为44 cm/s(范围20至62 cm/s)。所有速度均超过了非支架置入颈动脉DUS标准中50%狭窄的阈值。在3条动脉(2例患者)中,DUS检测到高级别再狭窄,在随访期间需要再次干预。每位患者的血管造影均证实了这种高级别再狭窄,又提供了3组相关性数据。
正常的DUS成像能够可靠地识别CAS术后血管造影正常的颈动脉。在轻度和中度狭窄时,颈动脉速度不成比例地升高,这些患者定量狭窄的速度标准需要修正。然而,DUS能够准确识别CAS术后严重的再狭窄。