平肠球菌Mur-2酶具有N-乙酰葡糖胺糖苷酶活性。
The Enterococcus hirae Mur-2 enzyme displays N-acetylglucosaminidase activity.
作者信息
Eckert Catherine, Magnet Sophie, Mesnage Stéphane
机构信息
INSERM, U655-LRMA, Centre de Recherches Biomédicales des Cordeliers, Paris, France.
出版信息
FEBS Lett. 2007 Feb 20;581(4):693-6. doi: 10.1016/j.febslet.2007.01.033. Epub 2007 Jan 22.
Abstract
Enterococcus hirae produces two autolytic enzymes named Mur-1 and Mur-2, both previously described as N-acetylmuramidases. We used tandem mass spectrometry to show that Mur-2 in fact displays N-acetylglucosaminidase activity. This result reveals that Mur-2 and its counterparts studied to date, which are members of glycosyl hydrolase family 73 from the CAZy (Carbohydrate-Active enZyme) database, display the same catalytic activity.
摘要
平肠球菌产生两种自溶酶，分别命名为Mur-1和Mur-2，这两种酶之前都被描述为N-乙酰胞壁酸酶。我们使用串联质谱法表明，Mur-2实际上具有N-乙酰葡糖胺酶活性。这一结果表明，Mur-2及其迄今研究的对应物，即来自CAZy（碳水化合物活性酶）数据库的糖基水解酶家族73的成员，具有相同的催化活性。
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