Frerich B, Ehrenfeld M, Cornelius C P, Wiethölter H, Schwenzer N, Donath K
Klinik und Poliklinik für Kiefer- und Geischtschirurgie Eberhard-Karls-Universität Tübingen.
Dtsch Zahnarztl Z. 1991 Jan;46(1):80-3.
A survey is given of patients with odontogenic keratocysts in childhood and adolescence which were treated at the Clinic for Maxillofacial Surgery Tübingen in the last 10 years. Odontogenic keratocysts occurring in the growth period are treated in most cases by enucleation or partial marsupialization. To avoid damaging the nerve or dental germs, fixation with Carnoy's solution is not performed. In a second part an experimental study dealing with the effects of Carnoy's solution on peripheral nerves is presented. After incubating the sciatic nerve of rats with Carnoy's solution lumbar SEP, M-response and Hoffmann's reflex were recorded. It was possible to demonstrate the detrimental effect of Carnoy's solution on peripheral nerves. After incubation periods of more than 2 minutes almost complete functional loss was observed. There was a strong correlation between electrophysiological and histological findings.
对过去10年在图宾根颌面外科诊所接受治疗的儿童和青少年牙源性角化囊肿患者进行了一项调查。生长期出现的牙源性角化囊肿在大多数情况下通过摘除或部分袋形缝合术进行治疗。为避免损伤神经或牙胚，不使用卡诺伊溶液进行固定。第二部分介绍了一项关于卡诺伊溶液对外周神经影响的实验研究。用卡诺伊溶液孵育大鼠坐骨神经后，记录腰段体感诱发电位（SEP）、肌肉反应（M反应）和霍夫曼反射。可以证明卡诺伊溶液对外周神经有有害作用。孵育超过2分钟后，观察到几乎完全的功能丧失。电生理和组织学结果之间存在很强的相关性。
