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眼内炎患者行眼球内容剜除术并一期植入义眼座

Evisceration with primary implant placement in patients with endophthalmitis.

作者信息

Tawfik Hatem A, Budin Hamida

机构信息

Department of Ophthalmology, Ain-Shams University, Cairo, Egypt.

出版信息

Ophthalmology. 2007 Jun;114(6):1100-3. doi: 10.1016/j.ophtha.2006.09.027. Epub 2007 Jan 29.

Abstract

PURPOSE

To assess the feasibility of evisceration with primary implant placement in patients with endophthalmitis.

DESIGN

Pilot retrospective study.

PARTICIPANTS

Sixty-seven patients with endophthalmitis.

METHODS

A retrospective study was conducted to review the files of 67 patients with endophthalmitis who underwent evisceration with primary implant placement over an 8-year period. These patients' files were reviewed to evaluate the following: persistent infection and inflammation, spread of infection to contiguous or remote sites, implant exposure or extrusion, and successful fitting of the prosthesis.

MAIN OUTCOME MEASURES

Quiescence of the infection, complete healing of the socket, and long-term retention of the implant.

RESULTS

Sixty-three patients successfully retained their primary implant with rapid resolution of infection and inflammation. In 1 patient, attempts at implant placement were abandoned during surgery because of marked scleral necrosis. Delayed implant extrusion was noted in 2 patients, 10 and 12 days after surgery, respectively. In 1 diabetic patient, an orbital abscess developed that was evacuated with implant exchange. In a fourth patient, marked conjunctival prolapse developed in the early postoperative period with eventual obliteration of the inferior fornix. The patient declined further management. Minor complications included a central conjunctival dehiscence or necrosis (n = 2) and a pyogenic granuloma that was excised (n = 1). All minor complications healed without sequelae. Overall, 12 % of patients experienced complications (n = 8).

CONCLUSIONS

Based on the low overall complication rate in the present study (12%), the ease of evisceration, the convenience of a single procedure, the rapid resolution of infection, and the successful retention of the implant in most of our patients, it is plausible to offer evisceration with primary implant placement to patients with recalcitrant endophthalmitis or panophthalmitis. This would avoid a secondary surgical intervention in most patients, as opposed to delayed secondary implantation, in which case 100% of the patients would require, at least theoretically, another intervention.

摘要

目的

评估眼内容剜除联合一期植入物植入术在眼内炎患者中的可行性。

设计

前瞻性回顾性研究。

研究对象

67例眼内炎患者。

方法

进行一项回顾性研究,回顾67例在8年期间接受眼内容剜除联合一期植入物植入术的眼内炎患者的病历。对这些患者的病历进行评估,以评价以下方面:持续性感染和炎症、感染扩散至相邻或远处部位、植入物暴露或脱出,以及义眼的成功适配。

主要观察指标

感染静止、眼窝完全愈合,以及植入物的长期留存。

结果

63例患者成功保留了一期植入物,感染和炎症迅速消退。1例患者在手术过程中因明显的巩膜坏死而放弃植入物植入尝试。2例患者分别在术后10天和12天出现延迟性植入物脱出。1例糖尿病患者发生眶内脓肿,通过更换植入物进行了引流。第4例患者在术后早期出现明显的结膜脱垂,最终下穹窿消失。该患者拒绝进一步治疗。轻微并发症包括中央结膜裂开或坏死(n = 2)和1例切除的化脓性肉芽肿。所有轻微并发症均愈合,无后遗症。总体而言,12%的患者出现并发症(n = 8)。

结论

基于本研究中较低的总体并发症发生率(12%)、眼内容剜除操作的简便性、单次手术的便利性、感染的快速消退以及大多数患者植入物的成功留存,对于难治性眼内炎或全眼球炎患者,提供眼内容剜除联合一期植入物植入术是合理的。这将避免大多数患者进行二次手术干预,与延迟二期植入相反,在延迟二期植入的情况下,至少在理论上100%的患者需要再次干预。

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