Kim Ju-Mi, Sung Jae-Yun, Lim Hyung-Bin, Choi Eun-Jung, Lee Sung-Bok
Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon 35015, Korea.
Department of Ophthalmology, Chungnam National University Sejong Hospital, Sejong 30099, Korea.
J Clin Med. 2021 Jul 28;10(15):3329. doi: 10.3390/jcm10153329.
This study analyzed risk factors for extrusion of orbital implants after evisceration by comparing patients with and without implant extrusion.
We retrospectively reviewed the medical records of patients who underwent evisceration with primary implant placement by a single surgeon from January 2005 to December 2019 at the Chungnam National University Hospital. Age, sex, underlying systemic diseases, axial length of the fellow eye, the cause of evisceration, endophthalmitis type, implant type and size, and preoperative computed tomography findings were evaluated. Logistic regression analysis was used to identify the risk factors for implant extrusion.
Of the 140 eyes of 140 patients, extrusion occurred in five eyes (3.6%). Endophthalmitis (odds ratio (OR), 15.49; 95% confidence interval (CI), 1.70 to 2038.56; = 0.010), endogenous endophthalmitis (OR, 18.73; 95% CI, 3.22 to 125.21, = 0.002), orbital cellulitis (OR, 320.54; 95% CI, 29.67 to 44801.64; < 0.001), implant size (OR, 0.50; 95% CI, 0.30 to 0.79; = 0.004), and hydroxyapatite for the implant (OR, 0.07; 95% CI, 0.00 to 0.66; = 0.016) were risk factors for implant extrusion in univariate logistic regression analysis. Multiple logistic regression analysis identified orbital cellulitis as the only risk factor for extrusion (OR, 52.98; 95% CI, 2.18 to 15367.34; = 0.009).
Evisceration with primary orbital implantation is a feasible option in endophthalmitis, but the risk of extrusion should be taken into consideration. When performing evisceration in a patient with orbital cellulitis, secondary implantation should be carried out only after any infection is controlled.
本研究通过比较有和没有植入物挤出的患者,分析了眼内容剜出术后眼眶植入物挤出的危险因素。
我们回顾性分析了2005年1月至2019年12月在忠南国立大学医院由单一外科医生进行眼内容剜出并一期植入植入物的患者的病历。评估了年龄、性别、潜在的全身性疾病、对侧眼的眼轴长度、眼内容剜出的原因、眼内炎类型、植入物类型和尺寸以及术前计算机断层扫描结果。采用逻辑回归分析来确定植入物挤出的危险因素。
140例患者的140只眼中,有5只眼(3.6%)发生了植入物挤出。在单因素逻辑回归分析中,眼内炎(比值比(OR),15.49;95%置信区间(CI),1.70至2038.56;P = 0.010)、内源性眼内炎(OR,18.73;95%CI,3.22至125.21,P = 0.002)、眼眶蜂窝织炎(OR,320.54;95%CI,29.67至44801.64;P < 0.001)、植入物尺寸(OR,0.50;95%CI,0.30至0.79;P = 0.004)以及植入物使用羟基磷灰石(OR,0.07;95%CI,0.00至0.66;P = 0.016)是植入物挤出的危险因素。多因素逻辑回归分析确定眼眶蜂窝织炎是挤出的唯一危险因素(OR,52.98;95%CI,2.18至15367.34;P = 0.009)。
眼内容剜出并一期眼眶植入在眼内炎中是一种可行的选择,但应考虑挤出的风险。在眼眶蜂窝织炎患者进行眼内容剜出时,仅应在任何感染得到控制后进行二期植入。