Szymański Henryk, Chmielarczyk Agnieszka, Strus Magdalena, Pejcz Jerzy, Jawień Mirosław, Kochan Piotr, Heczko Piotr B
Department of Pediatrics, St. Hedwigof Silesia Hospital, 53/55 Prusicka Street, 55-100 Trzebnica, Poland.
Dig Liver Dis. 2006 Dec;38 Suppl 2:S274-6. doi: 10.1016/S1590-8658(07)60009-7.
Lactobacillus rhamnosus (573L/1-3) strains are considered effective in the treatment of rotaviral diarrhoea in children. The colonisation of the gastrointestinal (G.I.) tract by the Lactobacillus rhamnosus strains and the determining factors are discussed reporting data of a prospective, double-blinded, placebo-controlled randomized study in children between the 2nd month and 6th year of life with acute diarrhoea lasting not longer than 5 days. The examined strains were detected in 37/46 (80.43%) patients after 5 days and in 19/46 (41.3%) patients after 14 days since the start of the treatment. L. rhamnosus 573L/1 strain colonised the G.I. tract more persistently. L. rhamnosus strains are effective in colonising the G.I. tract during acute diarrhoea. Persistence of colonisation is dependent on the properties of administered probiotic strains.
鼠李糖乳杆菌（573L/1-3）菌株被认为对治疗儿童轮状病毒腹泻有效。本文通过一项前瞻性、双盲、安慰剂对照的随机研究的数据，讨论了鼠李糖乳杆菌菌株在胃肠道（G.I.）的定植情况及决定因素，该研究针对2个月至6岁患有持续时间不超过5天的急性腹泻的儿童。治疗开始5天后，在46名患者中的37名（80.43%）检测到所检测的菌株，14天后在46名患者中的19名（41.3%）检测到。鼠李糖乳杆菌573L/1菌株在胃肠道的定植更持久。鼠李糖乳杆菌菌株在急性腹泻期间对胃肠道的定植有效。定植的持续性取决于所施用益生菌菌株的特性。
