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胰岛素给药后小鼠下丘脑RNA含量的变化。

Changes in RNA content of the hypothalamus of mice following insulin administration.

作者信息

Lach H, Srebro Z, Surowiak J

机构信息

Department of Animal Physiology, Teacher Training College, Kraków, Poland.

出版信息

Folia Biol (Krakow). 1991;39(1-4):49-52.

PMID:1725978
Abstract

Cytoplasmic total RNA in neurons of the supraoptic nucleus, paraventricular nucleus, suprachiasmatic nucleus, and arcuate nucleus was determined cytophotometrically following a single intramuscular dose of 4 IU/kg insulin semilente. A significant decrease was observed after 3, 6, and 12 hours. A return towards normal values was evident after 24 hours and was full after 48 hours only in suprachiasmatic nucleus. Other hypothalamic nuclei did not reach the full normal value in the time interval examined, i.e. 48 hours post-injection.

摘要

在肌肉注射单剂量4 IU/kg半慢胰岛素后,用细胞光度法测定视上核、室旁核、视交叉上核和弓状核神经元中的细胞质总RNA。在3小时、6小时和12小时后观察到显著下降。24小时后明显恢复到正常值,仅视交叉上核在48小时后完全恢复。在所检查的时间间隔内,即注射后48小时,其他下丘脑核未达到完全正常的值。

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