Mao Yi-lei, Zhang Tao
Department of Liver Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Dec;28(6):849-52.
Risks persists during liver resection in the patients with cirrhosis. Routine examinations usually are unable to predict the morbidity and mortality following surgery. Evaluation approaches of liver function, including aminotransferase, bilirubin, albumin, prothrombin time, Child-Pugh classification, and indocyanine green (ICG) test, currently remain the most important method to determine the prognosis of liver resection, especially in cirrhotic patients. However, all these approaches have their weakness. Some new methods, including non-invasive ICG test, liver function evaluation by hepatic imaging, and remnant hepatic function test, are awaiting further investigation. This article reviews the current status and future prospect in the assessment of liver functions.
肝硬化患者肝切除术中风险持续存在。常规检查通常无法预测术后的发病率和死亡率。肝功能评估方法,包括转氨酶、胆红素、白蛋白、凝血酶原时间、Child-Pugh分级和吲哚菁绿(ICG)试验,目前仍然是确定肝切除预后的最重要方法,尤其是在肝硬化患者中。然而,所有这些方法都有其局限性。一些新方法,包括非侵入性ICG试验、肝脏影像学评估肝功能和残余肝功能试验,尚有待进一步研究。本文综述了肝功能评估的现状和未来前景。