Bhattacharya S K, Maity P C, Mediratta P, Sen P
Department of Pharmacology, University College of Medical Sciences & GT Hospital, Delhi, India.
Indian J Exp Biol. 1991 Oct;29(10):971-2.
Effect of alkaloidal fraction of aqueous extract of T. malabarica (Tm) was studied on humoral antibody responses in rats and guineapigs. The anti-SRBC haemagglutination titre was found to be enhanced in rats pretreated with Tm (2.5 mg/kg). Passive cutaneous anaphylaxis (PCA) in rats was also increased in Tm treated group. In vitro experiments with sensitized rat peritoneal mast cells showed a significant decrease in antigen-induced various spasmogens on isolated guineapig ileum.
研究了马拉巴尔罗勒(Tm)水提取物的生物碱部分对大鼠和豚鼠体液抗体反应的影响。发现用Tm(2.5毫克/千克)预处理的大鼠抗绵羊红细胞血凝滴度有所提高。Tm治疗组大鼠的被动皮肤过敏反应(PCA)也有所增加。对致敏大鼠腹膜肥大细胞进行的体外实验表明,抗原诱导的各种致痉物质对离体豚鼠回肠的作用显著降低。