Tn1403，一种由三个不同转座子组成的多重抗生素抗性转座子。
Tn1403, a multiple-antibiotic resistance transposon made up of three distinct transposons.
作者信息
Stokes H W, Elbourne Liam D H, Hall Ruth M
机构信息
School of Molecular and Microbial Biosciences, Biochemistry and Microbiology Building G08, The University of Sydney, NSW, Australia.
出版信息
Antimicrob Agents Chemother. 2007 May;51(5):1827-9. doi: 10.1128/AAC.01279-06. Epub 2007 Jan 29.
Abstract
Transposon Tn1403 from a clinical Pseudomonas strain is composed of three transposons, including Tn5393c. A related transposon Tn1404* from a plant-associated Pseudomonas strain lacks Tn5393 but includes a transposon carrying the tet(C) tetracycline resistance determinant. These compound transposons illustrate the role of preexisting transposons in generating clusters of antibiotic resistance genes.
摘要
来自临床假单胞菌菌株的转座子Tn1403由三个转座子组成，包括Tn5393c。来自与植物相关的假单胞菌菌株的相关转座子Tn1404*缺乏Tn5393，但包括一个携带tet(C)四环素抗性决定簇的转座子。这些复合转座子说明了现有转座子在产生抗生素抗性基因簇中的作用。
相似文献
1
Tn1403, a multiple-antibiotic resistance transposon made up of three distinct transposons.
Antimicrob Agents Chemother. 2007 May;51(5):1827-9. doi: 10.1128/AAC.01279-06. Epub 2007 Jan 29.
2
Tn6001, a transposon-like element containing the blaVIM-3-harboring integron In450.
Antimicrob Agents Chemother. 2007 Nov;51(11):4187-90. doi: 10.1128/AAC.00542-07. Epub 2007 Sep 10.
3
[Characteristics of Tn3611 and Tn3613 transposons discovered in the chromosome of the BS205 strain of Pseudomonas aeruginosa].
Genetika. 1988 May;24(5):781-90.
4
Transposon Tn5393e carrying the aphA1-containing transposon Tn6023 upstream of strAB does not confer resistance to streptomycin.
Microb Drug Resist. 2011 Sep;17(3):389-94. doi: 10.1089/mdr.2011.0037. Epub 2011 Jun 24.
5
[Screen and identification of genes involved in multidrug resistance in Pseudomonas aeruginosa].
Wei Sheng Wu Xue Bao. 2008 Aug;48(8):1019-24.
6
Tn6060, a transposon from a genomic island in a Pseudomonas aeruginosa clinical isolate that includes two class 1 integrons.
Antimicrob Agents Chemother. 2009 Dec;53(12):5294-6. doi: 10.1128/AAC.00687-09. Epub 2009 Sep 14.
7
Molecular characterization of the class II multiresistance transposable element Tn1403 from Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1991 Feb;35(2):313-21. doi: 10.1128/AAC.35.2.313.
8
Acquisition of multidrug resistance transposon Tn6061 and IS6100-mediated large chromosomal inversions in Pseudomonas aeruginosa clinical isolates.
Microbiology (Reading). 2010 May;156(Pt 5):1448-1458. doi: 10.1099/mic.0.033639-0. Epub 2010 Jan 28.
9
The structure and expression of the mercury-resistance transposon Tn501.
Folia Biol (Praha). 1984;30 Spec No:7-17.
10
Detection of a genetic linkage between genes coding for resistance to tetracycline and erythromycin in Clostridium difficile.
Microb Drug Resist. 2007 Summer;13(2):90-5. doi: 10.1089/mdr.2007.723.
引用本文的文献
1
Evolution of XDR ST463 strains with two plasmids harboring multiple antimicrobial resistance genes.
Antimicrob Agents Chemother. 2025 Sep 3;69(9):e0169724. doi: 10.1128/aac.01697-24. Epub 2025 Jul 23.
2
High prevalence of carbapenem-resistant and identification of a novel VIM-type metallo-β-lactamase, VIM-92, in clinical isolates from northern China.
Front Microbiol. 2025 Feb 26;16:1543509. doi: 10.3389/fmicb.2025.1543509. eCollection 2025.
3
Genetic Characteristics of Novel Inc Plasmids, Integrative and Mobilizable Elements, and Integrative and Conjugative Elements in .
Infect Drug Resist. 2024 May 25;17:2053-2068. doi: 10.2147/IDR.S462670. eCollection 2024.
4
IS and the IS family: versatile resistance gene movers and genome reorganizers.
Microbiol Mol Biol Rev. 2024 Jun 27;88(2):e0011922. doi: 10.1128/mmbr.00119-22. Epub 2024 Mar 4.
5
Uncovering the hidden threat: The widespread presence of chromosome-borne accessory genetic elements and novel antibiotic resistance genetic environments in .
Virulence. 2023 Dec;14(1):2271688. doi: 10.1080/21505594.2023.2271688. Epub 2023 Oct 27.
6
Characterization of two novel VIM-type metallo-β-lactamases, VIM-84 and VIM-85, associated with the spread of IncP-2 megaplasmids in .
Microbiol Spectr. 2023 Sep 14;11(5):e0154423. doi: 10.1128/spectrum.01544-23.
7
Abundant diversity of accessory genetic elements and associated antimicrobial resistance genes in pseudomonas aeruginosa isolates from a single Chinese hospital.
Ann Clin Microbiol Antimicrob. 2023 Jun 29;22(1):51. doi: 10.1186/s12941-023-00600-3.
8
Characterization of Three Novel IMP Metallo-β-Lactamases, IMP-89, IMP-91, and IMP-96, and Diverse -Carrying Accessory Genetic Elements from Chinese Clinical Isolates.
Microbiol Spectr. 2023 Jun 15;11(3):e0498622. doi: 10.1128/spectrum.04986-22. Epub 2023 Apr 19.
9
Coexistence of tigecycline resistance genes with two novel -carrying and -carrying transposons in a plasmid.
Front Cell Infect Microbiol. 2023 Mar 1;13:1130333. doi: 10.3389/fcimb.2023.1130333. eCollection 2023.
10
Emerging and re-emerging KPC-producing hypervirulent ST697 and ST463 between 2010 and 2021.
Emerg Microbes Infect. 2022 Dec;11(1):2735-2745. doi: 10.1080/22221751.2022.2140609.
本文引用的文献
1
Antibiotic resistance in gram-negative bacteria: the role of gene cassettes and integrons.
Drug Resist Updat. 1998;1(2):109-19. doi: 10.1016/s1368-7646(98)80026-5.
2
Complex multiple antibiotic and mercury resistance region derived from the r-det of NR1 (R100).
Antimicrob Agents Chemother. 2004 Nov;48(11):4250-5. doi: 10.1128/AAC.48.11.4250-4255.2004.
3
Complete sequence and genetic organization of pDTG1, the 83 kilobase naphthalene degradation plasmid from Pseudomonas putida strain NCIB 9816-4.
J Mol Biol. 2004 Aug 13;341(3):753-68. doi: 10.1016/j.jmb.2004.06.034.
4
Complete nucleotide sequence and organization of the naphthalene catabolic plasmid pND6-1 from Pseudomonas sp. strain ND6.
Gene. 2004 Jul 21;336(2):231-40. doi: 10.1016/j.gene.2004.03.027.
5
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
Antimicrob Agents Chemother. 2003 Jan;47(1):342-9. doi: 10.1128/AAC.47.1.342-349.2003.
6
Class 1 integron containing a new gene cassette, aadA10, associated with Tn1404 from R151.
Antimicrob Agents Chemother. 2002 Aug;46(8):2400-8. doi: 10.1128/AAC.46.8.2400-2408.2002.
7
Family of class 1 integrons related to In4 from Tn1696.
Antimicrob Agents Chemother. 2001 Nov;45(11):3014-20. doi: 10.1128/AAC.45.11.3014-3020.2001.
8
Identification and characterization of Tn4656, a novel class II transposon carrying a set of toluene-degrading genes from TOL plasmid pWW53.
J Bacteriol. 2001 Nov;183(21):6215-24. doi: 10.1128/JB.183.21.6215-6224.2001.
9
Functional Tn5393-like transposon in the R plasmid pRAS2 from the fish pathogen Aeromonas salmonicida subspecies salmonicida isolated in Norway.
Appl Environ Microbiol. 2000 Dec;66(12):5533-5. doi: 10.1128/AEM.66.12.5533-5535.2000.
10
Distribution of tetracycline resistance genes and transposons among phylloplane bacteria in Michigan apple orchards.
Appl Environ Microbiol. 1999 Nov;65(11):4898-907. doi: 10.1128/AEM.65.11.4898-4907.1999.
Zotero 插件