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[Meige综合征病程中的痉挛性发声障碍——病例报告]

[Spasmodic dysphonia in course of Meige's syndrome--case report].

作者信息

Zalesska-Krecicka Maria, Morawska-Kochman Monika, Wierzbicka Ewa, Skrzypek Aleksandra, Krecicki Tomasz

机构信息

Katedra i Klinika Otolaryngologii AM we Wrocławiu.

出版信息

Otolaryngol Pol. 2006;60(5):779-81.

PMID:17263254
Abstract

INTRODUCTION

The Meige's syndrom is characterized by the presence of bilateral, symmetrical, dystonic cramp of face muscles or muscles of middle line of body, the respiratory muscles and muscles of throat. The etiology of Meige's syndrome is uncertain. The disorders of basal ganglia function and neurotransmitters' imbalance (dopamine and acetylocholine) can be with reason of pronouncement of symptoms presumably.

MATERIAL AND METHOD

Our aim was to introduce a case of 71 years old patient in whom we diagnosed spasmodic dysphonia in course of Meige's Syndrom. Patient has been treated by 3 years with Botulin toxin. The spasmodic Dysphonia occurred after over 2 years from appearing of first syndrom's symptoms.

RESULTS

Sonorous voice during rehabilitation was got during expressing syllables and short bisyllabic words. Patient stays still under phoniatric care.

CONCLUSIONS

Patients with spasmodic dysphonia ought to be examined by a interdisciplinary medical team.

摘要

引言

梅杰综合征的特征是双侧、对称的面部肌肉或身体中线肌肉、呼吸肌及咽喉肌的肌张力障碍性痉挛。梅杰综合征的病因尚不确定。基底神经节功能障碍和神经递质失衡(多巴胺和乙酰胆碱)可能是症状发作的原因。

材料与方法

我们的目的是介绍一例71岁患者,我们在其梅杰综合征病程中诊断出痉挛性发声障碍。该患者接受肉毒毒素治疗3年。痉挛性发声障碍在首次出现综合征症状2年多后发生。

结果

在康复过程中,患者在发单音节和短双音节词时声音洪亮。患者仍在接受语音治疗。

结论

痉挛性发声障碍患者应由跨学科医疗团队进行检查。

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1
[Spasmodic dysphonia in course of Meige's syndrome--case report].[Meige综合征病程中的痉挛性发声障碍——病例报告]
Otolaryngol Pol. 2006;60(5):779-81.
2
Neurologic aspects of spasmodic dysphonia.痉挛性发声障碍的神经学方面
J Otolaryngol. 1990 Aug;19(4):231-6.
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Five-year experience in the treatment of focal movement disorders with low-dose Dysport botulinum toxin.低剂量Dysport肉毒杆菌毒素治疗局灶性运动障碍的五年经验。
Muscle Nerve. 1995 Jul;18(7):720-9. doi: 10.1002/mus.880180708.
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[Treatment of spasmodic dysphonia with botulinum toxin].[肉毒杆菌毒素治疗痉挛性发声障碍]
Ann Otolaryngol Chir Cervicofac. 1991;108(8):477-82; discussion 482-3.
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Double-blind controlled study of botulinum toxin in adductor spasmodic dysphonia.肉毒杆菌毒素治疗内收型痉挛性发音障碍的双盲对照研究。
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Levetiracetam in Meige's syndrome.左乙拉西坦治疗梅杰综合征
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Use of botulinum toxin in Meige's disease.肉毒杆菌毒素在Meige病中的应用。
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[Botulinum toxin A in therapy of craniocervical dystonias and hemifacial spasm].[A型肉毒毒素治疗颅颈肌张力障碍和半面痉挛]
Acta Med Austriaca. 1991;18(5):125-9.
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Botulinum toxin in the treatment of adductor spasmodic dysphonia.肉毒杆菌毒素治疗内收型痉挛性发声障碍
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Meige's syndrome: A cranial dystonia treated with bilateral pallidal deep brain stimulation.梅杰综合征:一种采用双侧苍白球深部脑刺激术治疗的颅肌张力障碍。
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