两种新型二羧酸衍生物及一种来自核桃的新型二聚体可水解单宁。

Two novel dicarboxylic Acid derivatives and a new dimeric hydrolyzable tannin from walnuts.

作者信息

Ito Hideyuki, Okuda Takahiro, Fukuda Toshiyuki, Hatano Tsutomu, Yoshida Takashi

机构信息

Department of Pharmacognosy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tsushima, Okayama 700-8530, Japan.

出版信息

J Agric Food Chem. 2007 Feb 7;55(3):672-9. doi: 10.1021/jf062872b.

DOI:10.1021/jf062872b

PMID:17263459

Abstract

In addition to the 16 previously reported polyphenols including 3 new ellagitannins, 2 novel dicarboxylic acid derivatives, glansreginins A (1) and B (2), and a new dimeric hydrolyzable tannin, glansrin D (3), were isolated, together with 15 known compounds from walnuts, the seeds of Juglans regia. The structures of the new compounds were elucidated on the basis of 1D- and 2D-NMR analyses and chemical data. The antioxidant effect of these isolates was also evaluated by SOD-like and DPPH radical scavenging activities.

摘要

除了之前报道的16种多酚类物质（包括3种新的鞣花单宁、2种新型二羧酸衍生物、胡桃素A（1）和B（2）以及一种新的二聚体可水解单宁胡桃素D（3））之外，还从胡桃（Juglans regia）种子的核桃中分离出15种已知化合物。通过一维和二维核磁共振分析以及化学数据阐明了这些新化合物的结构。还通过超氧化物歧化酶样和二苯基苦味酰基自由基清除活性评估了这些分离物的抗氧化作用。