Weiss Markus, Shorten George, Stutz Katharina, Bernet Vera
Department of Anaesthesia, University Children's Hospital, Zurich, Switzerland.
Paediatr Anaesth. 2007 Mar;17(3):243-8. doi: 10.1111/j.1460-9592.2006.02064.x.
The purpose of this study was to determine if inspiratory pressure from intermittent positive pressure ventilation may be sufficient to inflate the cuff (thus 'auto-inflation') and thereby seal the trachea.
In a laboratory model we investigated the ability of cuffs of seven 5.0 mm internal diameter (ID) tracheal tubes (Sheridan CF, Mallinckrodt Hi-Contour, Mallinckrodt Sealguard, Mallinckrodt Safety-Flex, Portex Soft Seal, Rueschelit Super-Safety Clear and Microcuff PET) to seal the trachea by auto-inflation, i.e. by using the inspiratory pressure to expand and keep open the cuff within the trachea. A mechanical lung connected to a model trachea made from clear, rigid polyvinylchloride (PVC) (12 mm ID) was used to simulate changes in inspiratory pressures. Respirator settings were: fresh gas flow (air) 6 lxmin(-1); positive end-expiratory pressure 5 cmH(2)O; respiratory rate 20 brxmin(-1); I : E ratio = 1 : 2; inspiratory pressure 5, 10, 15, 20, and 25 cmH(2)O. Percentage of expiratory to inspiratory tidal volume (E : I V(t) volume ratio) was calculated.
Using lubricated Mallinckrodt Seal Guard tube cuffs E : I V(t) volume ratio was almost 100% at a peak inspiratory pressure of 10 cmH(2)o whereas in tube cuffs particularly made of PVC an E : I ratio was achieved only at higher inspiratory pressures, if at all.
Auto-inflation in the Mallinckrodt Seal Guard with high volume-low pressure polyurethane cuff can produce adequate tracheal sealing in the model trachea used. The implication is that such auto-inflation should decrease the risk of tracheal injury from acute or persistent cuff hyperinflation.
本研究的目的是确定间歇性正压通气产生的吸气压力是否足以使气管插管的套囊充气(即“自动充气”),从而密封气管。
在一个实验室模型中,我们研究了7根内径为5.0毫米(ID)的气管导管(Sheridan CF、Mallinckrodt Hi-Contour、Mallinckrodt Sealguard、Mallinckrodt Safety-Flex、Portex Soft Seal、Rueschelit Super-Safety Clear和Microcuff PET)的套囊通过自动充气来密封气管的能力,即利用吸气压力使套囊在气管内膨胀并保持张开。使用一个连接到由透明硬质聚氯乙烯(PVC)(内径12毫米)制成的气管模型的机械肺来模拟吸气压力的变化。呼吸机设置为:新鲜气体流量(空气)6升/分钟;呼气末正压5厘米水柱;呼吸频率20次/分钟;吸呼比=1:2;吸气压力5、10、15、20和25厘米水柱。计算呼气潮气量与吸气潮气量的百分比(E:I V(t)体积比)。
使用润滑后的Mallinckrodt Seal Guard气管导管套囊,在吸气峰值压力为10厘米水柱时,E:I V(t)体积比几乎为100%,而对于特别是由PVC制成的气管导管套囊,只有在更高的吸气压力下(如果有的话)才能达到E:I比。
带有大容量低压聚氨酯套囊的Mallinckrodt Seal Guard气管导管的自动充气在所用的气管模型中可产生足够的气管密封。这意味着这种自动充气应能降低因急性或持续性套囊过度充气导致气管损伤的风险。