Bernet V, Dullenkopf A, Cannizzaro V, Stutz K, Weiss M
Department of Neonatology and Intensive Care Medicine, University Children's Hospital, Zurich, Switzerland.
Anaesthesia. 2006 Oct;61(10):978-83. doi: 10.1111/j.1365-2044.2006.04785.x.
Cuff volume-pressure curves and cuff pressure-tracheal wall pressure relationships were investigated in eight brands of currently available cuffed, paediatric tracheal tubes with internal diameters of 5.0 mm. Cuff volume-pressure curves were measured with the cuff unrestricted and with the cuff placed within a tracheal model with wall pressure measurements. With the tracheal tube cuffs, unrestricted cuff compliance at 20 cmH(2)O cuff pressure varied between 0.06 and 0.3 ml x cmH(2)O(-1). With the cuff restricted within the model trachea, all tracheal tube cuffs became considerably less compliant (0.01-0.09 ml x cmH(2)O(-1)). We found tracheal wall pressure was similar to the cuff pressure as long as the resulting cuff diameter was sufficiently large freely to drape the inner tracheal wall. We found that, regardless of whether a higher or lower compliant tube cuff was used, cuff hyperinflation uniformly resulted in potentially compromised tracheal mucosal blood flow; cuff pressure monitoring using cuff pressure limitation is therefore strongly recommended.
对8个品牌目前市售的内径为5.0毫米的带套囊小儿气管导管,研究了套囊容积-压力曲线以及套囊压力-气管壁压力关系。套囊容积-压力曲线在套囊无限制以及套囊置于带有壁压力测量的气管模型内的情况下进行测量。对于气管导管套囊,在20 cmH₂O套囊压力下无限制套囊顺应性在0.06至0.3 ml·cmH₂O⁻¹之间变化。当套囊限制在模型气管内时,所有气管导管套囊的顺应性均显著降低(0.01至0.09 ml·cmH₂O⁻¹)。我们发现,只要由此产生的套囊直径足够大以自由覆盖气管内壁,气管壁压力就与套囊压力相似。我们发现,无论使用顺应性较高还是较低的导管套囊,套囊过度充气均会一致导致气管黏膜血流可能受损;因此强烈建议使用套囊压力限制进行套囊压力监测。