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杜氏利什曼原虫引起的慢性腹泻和吸收不良

Chronic diarrhea and malabsorption caused by Leishmania donovani.

作者信息

Baba Chalamalasetty Sreenivasa, Makharia Govind K, Mathur Purva, Ray Ruma, Gupta Siddhartha Datta, Samantaray J C

机构信息

Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110 029, India.

出版信息

Indian J Gastroenterol. 2006 Nov-Dec;25(6):309-10.

Abstract

Chronic diarrhea and malabsorption are uncommon in immunocompetent patients with visceral leishmaniasis. We report two immunocompetent patients with visceral leishmaniasis where the predominant presentation was chronic diarrhea. One of them had clinically overt malabsorption and duodenal mucosa was loaded with Leishmania donovani bodies. The other patient had diffuse colonic aphthous and discrete ulcerations and Leishmania donovani bodies were seen in the crush smears of the colonic mucosa. With amphotericin B, there was reversal of malabsorption and healing of colonic ulcers.

摘要

慢性腹泻和吸收不良在内脏利什曼病的免疫功能正常患者中并不常见。我们报告了两名免疫功能正常的内脏利什曼病患者,其主要表现为慢性腹泻。其中一名患者有明显的临床吸收不良,十二指肠黏膜充满杜氏利什曼原虫小体。另一名患者有弥漫性结肠阿弗他溃疡和散在溃疡,在结肠黏膜压片中可见杜氏利什曼原虫小体。使用两性霉素B后,吸收不良得到逆转,结肠溃疡愈合。

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