Department of Pharmacognosy, University of Istanbul, Istanbul, Turkey.
Planta Med. 1988 Jun;54(3):243-5. doi: 10.1055/s-2006-962417.
The distributions of the alkaloids colchicine, 2-demethylcolchicine, 3-demethylcolchicine, demecolcine, 2-demethyldemecolcine, and 3-demethyldemecolcine in the corms, stems, leaves, flowers, and seeds of COLCHICUM CILICICUM were analysed by HPLC. In addition, the alkaloids cornigerine, N-formyl- N-deacetylcolchicine, N-methyl-demecolcine, beta-lumicolchicine, gamma-lumicolchicine, beta-lumidemecolcine, gamma-lumidemecolcine, and N-ethoxycarbonyldemecolcine were identified, the last named being reported for the first time from a COLCHICUM species. The flavones luteolin and apigenin were isolated and benzoic, 2-hydroxy-6-methoxybenzoic, and vanillic acids were also detected.
采用高效液相色谱法分析了藏黄莲（COLCHICUM CILICICUM）球茎、茎、叶、花和种子中生物碱秋水仙碱、2-去甲基秋水仙碱、3-去甲基秋水仙碱、美克秋水仙碱、2-去甲美克秋水仙碱和 3-去甲美克秋水仙碱的分布。此外，还鉴定了角秋水仙碱、N-甲酰基-N-去乙酰秋水仙碱、N-甲基美克秋水仙碱、β-秋水仙碱、γ-秋水仙碱、β-秋水仙酰胺、γ-秋水仙酰胺和 N-乙氧羰基美克秋水仙碱，其中最后一种生物碱为首次从 COLCHICUM 属植物中分离得到。分离得到黄酮类化合物木樨草素和芹菜素，并检测到苯甲酸、2-羟基-6-甲氧基苯甲酸和香草酸。
