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[自体血液预存式献血及围手术期促红细胞生成素的应用]

[Autologous blood pre-donation and perioperative use of erythropoietin].

作者信息

Michaeli Burkhard, Ravussin Patrick, Chassot Pierre-Guy

机构信息

Département d'anesthésiologie et de réanimation CHCVs, 1950 Sion.

出版信息

Rev Med Suisse. 2006 Nov 22;2(88):2662-4, 2666-7.

PMID:17265804
Abstract

The general concept of blood saving covers a number of technical and pharmacological actions which all aim to maintain the erythrocyte mass of the patient, and of which blood transfusion is only one. Severe anemia (Hb <60-80 g/l) increases postoperative mortality and morbidity. However, its correction by blood transfusion tends to worsen the prognosis. It is therefore imperative to conserve the patient's blood by any means possible. Detecting anemia is of primary importance. Whenever possible, its cause should be identified and treated. Depending on the detected anemia, as well as the blood loss expected during surgery, the patient should receive EPO (anemia with foreseeable moderate blood loss), or autologous pre-donation associated with EPO (anemia with foreseeable large blood loss).

摘要

血液保护的总体概念涵盖了许多技术和药理学措施,所有这些措施的目的都是维持患者的红细胞量,而输血只是其中之一。严重贫血(血红蛋白<60-80 g/l)会增加术后死亡率和发病率。然而,通过输血纠正贫血往往会使预后恶化。因此,必须尽可能地保存患者的血液。检测贫血至关重要。只要有可能,就应确定并治疗其病因。根据检测到的贫血情况以及手术期间预计的失血量,患者应接受促红细胞生成素(预计有中度失血的贫血),或与促红细胞生成素联合的自体预存献血(预计有大量失血的贫血)。

相似文献

1
[Autologous blood pre-donation and perioperative use of erythropoietin].[自体血液预存式献血及围手术期促红细胞生成素的应用]
Rev Med Suisse. 2006 Nov 22;2(88):2662-4, 2666-7.
2
[Effect of recombinant human erythropoietin on autologous blood pre-donation in open heart surgery].
Kyobu Geka. 1991 Aug;44(9):728-31.
3
Perioperative anemia.围手术期贫血
Surg Clin North Am. 2005 Dec;85(6):1215-27, x. doi: 10.1016/j.suc.2005.10.012.
4
Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative anaemia after knee replacement surgery.围手术期静脉注射铁剂可保存铁储备,并可能加速膝关节置换术后贫血的恢复。
Transfus Med. 2006 Oct;16(5):335-41. doi: 10.1111/j.1365-3148.2006.00682.x.
5
[Usefulness of recombinant human erythropoietin in cardiac surgery with autologous blood transfusion].重组人促红细胞生成素在自体输血心脏手术中的应用价值
Nihon Kyobu Geka Gakkai Zasshi. 1991 Dec;39(12):2140-4.
6
[Permissive anemia].[允许性贫血]
Zentralbl Chir. 2003 Jun;128(6):468-71. doi: 10.1055/s-2003-40619.
7
Use of recombinant human erythropoietin to enhance autologous blood donation in a patient with multiple red cell allo-antibodies and the anemia of chronic disease.
Am J Med. 1991 Mar;90(3):398-400.
8
Orthopaedic-induced anemia: the fallacy of autologous donation programs.骨科手术导致的贫血:自体献血项目的谬误
Clin Orthop Relat Res. 2005 Feb(431):145-9.
9
[Tolerance to perioperative anemia. Mechanisms, influencing factors and limits].[围手术期贫血耐受性。机制、影响因素及局限性]
Orthopade. 2007 Aug;36(8):763-76; quiz 777-8. doi: 10.1007/s00132-007-1126-z.
10
Optimizing autologous blood donation by recombinant human erythropoietin (rhu-EPO) and interleukin 3 (IL-3).通过重组人促红细胞生成素(rhu-EPO)和白细胞介素3(IL-3)优化自体献血。
Behring Inst Mitt. 1991 Dec(90):75-85.

引用本文的文献

1
Increased preoperative collection of autologous blood with recombinant human erythropoietin therapy in tertiary care hospitals of Jammu.查谟三级护理医院采用重组人促红细胞生成素疗法增加术前自体血采集量。
Asian J Transfus Sci. 2013 Jan;7(1):42-7. doi: 10.4103/0973-6247.106733.
2
[Anemia and transfusion therapy: an update].[贫血与输血治疗:最新进展]
Med Intensiva. 2011 Jan-Feb;35(1):32-40. doi: 10.1016/j.medin.2010.03.013. Epub 2010 May 18.