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[原发性动脉高血压女性孕早期胎盘的退行性变化]

[Regressive changes in the placenta in early pregnancy in women with primary arterial hypertension].

作者信息

Lotocki W, Król E, Drozdzewicz M

机构信息

Kliniki Ginekologii i Połoznictwa Septycznego, Instytutu Połoznictwa i Chorób Kobiecych AM Białymstoku.

出版信息

Rocz Akad Med Bialymst (1989). 1990;35-36:71-9.

PMID:1726680
Abstract

Morphological methods, in particular histochemical technique of secondary fluorescence according to Bertalanffy were used for the assessment of regressive changes of placenta. In women with primary arterial hypertension during early pregnancy fibrinoid masses in decidua, chorion, anchoring willi, villous plate, basal plate, villous trunks and terminal villi appear. These changes are followed from one side, by an atrophy of the blood vessels and connective tissue cells, and from the other, there increases the number of decidua giant cells, as well as of syncytium and cytotrophoblast. The areas of impaired blood supply contain giant cells and intervening foam cells. These cells according to the authors can be the forms of regressive changes exhibiting relative biological activity influencing trophic status of the placenta. Possible importance of the fibrinoid masses for the immunology of pregnancy which is developing under maternal morbid conditions has been discussed.

摘要

采用形态学方法,特别是根据贝塔朗菲的二次荧光组织化学技术,对胎盘的退行性变化进行评估。在妊娠早期患有原发性动脉高血压的女性中,蜕膜、绒毛膜、固定绒毛、绒毛板、基底板、绒毛干和终末绒毛中会出现类纤维蛋白团块。这些变化一方面表现为血管和结缔组织细胞萎缩,另一方面,蜕膜巨细胞、合体滋养层细胞和细胞滋养层细胞数量增加。血液供应受损区域含有巨细胞和中间泡沫细胞。作者认为,这些细胞可能是退行性变化的形式,具有相对的生物活性,影响胎盘的营养状态。文中还讨论了类纤维蛋白团块对在母体患病情况下发育的妊娠免疫学可能具有的重要性。

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