亨廷顿舞蹈症——建立联系 - Suppr

Suppr

超能文献

Huntington's disease--making connections.

作者信息

Greenamyre J Timothy

机构信息

Pittsburgh Institute for Neurodegenerative Diseases and the Department of Neurology, University of Pittsburgh, USA.

出版信息

N Engl J Med. 2007 Feb 1;356(5):518-20. doi: 10.1056/NEJMcibr067022.

DOI:10.1056/NEJMcibr067022

PMID:17267914

Abstract

摘要

相似文献

Huntington's disease--making connections.

N Engl J Med. 2007 Feb 1;356(5):518-20. doi: 10.1056/NEJMcibr067022.

PGC-1alpha, a new therapeutic target in Huntington's disease?

Cell. 2006 Nov 3;127(3):465-8. doi: 10.1016/j.cell.2006.10.023.

Transcription meets metabolism in neurodegeneration.

Nat Med. 2006 Nov;12(11):1239-41. doi: 10.1038/nm1106-1239.

Huntingtin-protein interactions and the pathogenesis of Huntington's disease.

Trends Genet. 2004 Mar;20(3):146-54. doi: 10.1016/j.tig.2004.01.008.

Suppression of aggregate formation of mutant huntingtin potentiates CREB-binding protein sequestration and apoptotic cell death.

Mol Cell Neurosci. 2012 Feb;49(2):127-37. doi: 10.1016/j.mcn.2011.11.003. Epub 2011 Nov 20.

The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease.

Biochim Biophys Acta. 2011 Sep;1812(9):1111-20. doi: 10.1016/j.bbadis.2011.05.006. Epub 2011 May 30.

Characterising the Huntington's disease gene product.

Biochem Soc Trans. 1995 Nov;23(4):595S. doi: 10.1042/bst023595s.

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.

Cell Metab. 2006 Nov;4(5):349-62. doi: 10.1016/j.cmet.2006.10.004. Epub 2006 Oct 19.

Neurodegeneration. A glutamine-rich trail leads to transcription factors.

Science. 2002 Jun 21;296(5576):2149-50. doi: 10.1126/science.1073845.

Peroxisome proliferator-activated receptor-γ cofactors in neurodegeneration.

IUBMB Life. 2012 Dec;64(12):958-64. doi: 10.1002/iub.1097. Epub 2012 Nov 6.

引用本文的文献

Neuroinflammation in Neurodegenerative Disorders: Current Knowledge and Therapeutic Implications.

Int J Mol Sci. 2024 Apr 3;25(7):3995. doi: 10.3390/ijms25073995.

Mitochondrial dysfunction in neurodegenerative disorders.

Neurotherapeutics. 2024 Jan;21(1):e00292. doi: 10.1016/j.neurot.2023.10.002. Epub 2023 Dec 19.

Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species.

Sci Rep. 2018 Jun 22;8(1):9554. doi: 10.1038/s41598-018-27900-5.

High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria.

Sci Rep. 2018 Jan 8;8(1):59. doi: 10.1038/s41598-017-17878-x.

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.

Sci Transl Med. 2012 Jul 11;4(142):142ra97. doi: 10.1126/scitranslmed.3003799.

PGC-1α at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond.

Prog Neurobiol. 2012 May;97(2):142-51. doi: 10.1016/j.pneurobio.2011.10.004. Epub 2011 Nov 9.

The role of mitochondria in neurodegenerative diseases.

J Neurol. 2011 Oct;258(10):1763-74. doi: 10.1007/s00415-011-6104-z. Epub 2011 May 22.

The right to ignore genetic status of late onset genetic disease in the genomic era; Prenatal testing for Huntington disease as a paradigm.

Am J Med Genet A. 2010 Jul;152A(7):1774-80. doi: 10.1002/ajmg.a.33432.

The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease.

J Bioenerg Biomembr. 2010 Jun;42(3):199-205. doi: 10.1007/s10863-010-9286-7.

A neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases.

PLoS One. 2010 Feb 2;5(2):e9002. doi: 10.1371/journal.pone.0009002.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验