[Effect of pH on the properties of the chemostatic culture of Canida utilis].

The effect of hydrogen and hydroxyl ions on the physiological features of the yeast C. utilis VKMU-1668 was studied. High acidity inhibited yeast growth and uncoupled pathways of the energy and constructive metabolism: normal respiration was disturbed and the electron transport chain was damaged in the site of cytochromes and not flavins. Hydroxyl ions also inhibited yeast growth and uncoupled pathways of the energy and constructive metabolism: oxygen uptake and the content of flavin adenone dinucleotide increased, dehydrogenase activity upon the use of glycerol decreased significantly, and the absolute amount of all cytochromes declined slightly. The chemical composition of cellular polymers at all pH values tested was stable enough. The amount of major metabolites--volatile oils and ketoacids--was insignificant.