Barros João Adriano, Valladares Geraldo, Faria Adriane Reichert, Fugita Erika Megumi, Ruiz Ana Paula, Vianna André Gustavo Daher, Trevisan Guilherme Luís, de Oliveira Fabrício Augusto Martinelli
Pulmonary Function Laboratory, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
J Bras Pneumol. 2006 May-Jun;32(3):221-7.
To evaluate confirmed cases of lung cancer, reviewing epidemiological variables, clinical variables, staging and treatment.
The cases of 263 patients were studied. All of the patients had been treated at the Universidade Federal do Paraná (Federal University of Paraná) Hospital de Clínicas or at the Hospital Erasto Gaertner, two institutions that, together, serve a significant portion of the patients seeking treatment in the city of Curitiba, located in the state of Paraná. This was a retrospective study, involving the administration of questionnaires. The descriptive analysis of the data obtained was performed using the Epi-Info program.
There was a predominance of male patients (76%). At the time of diagnosis, the majority of patients (90%) were smokers or former smokers. In 87% of the cases, there was no history of lung disease. The most common initial symptoms were cough (142 cases) and chest pain (92 cases). Non-small cell lung cancer was found in 87% of the patients, and the most common histological type was spinocellular carcinoma, which was found in 49% of all of the patients. Smoking was found to be the most significant predisposing factor.
The characteristics of lung cancer progression, such as the nonspecificity of the initial symptoms, the duration of tumor growth and the course of the tumor, together with the lack of tracking programs, are the principal factors that hinder the early detection of lung cancer, making it difficult to treat lung cancer patients and to increase their survival.
评估确诊的肺癌病例，回顾流行病学变量、临床变量、分期及治疗情况。
对263例患者的病例进行研究。所有患者均在巴拉那联邦大学临床医院或埃拉斯托·盖特纳医院接受治疗，这两家机构共同为巴拉那州库里蒂巴市大部分寻求治疗的患者提供服务。这是一项回顾性研究，采用问卷调查的方式。使用Epi-Info程序对获得的数据进行描述性分析。
男性患者占多数（76%）。在诊断时，大多数患者（90%）为吸烟者或既往吸烟者。87%的病例无肺部疾病史。最常见的初始症状是咳嗽（142例）和胸痛（92例）。87%的患者被诊断为非小细胞肺癌，最常见的组织学类型是棘细胞癌，在所有患者中占49%。吸烟被认为是最重要的诱发因素。
肺癌进展的特征，如初始症状的非特异性、肿瘤生长的持续时间和肿瘤病程，以及缺乏追踪项目，是阻碍肺癌早期发现的主要因素，使得治疗肺癌患者并提高其生存率变得困难。
