Watson D G, McGhee C N, Midgley J M, Zhou P, Doig W M
Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, Scotland, U.K.
J Neurochem. 1992 Jan;58(1):116-20. doi: 10.1111/j.1471-4159.1992.tb09285.x.
The concentrations of acidic metabolites derived from the biogenic amines o-, m-, and p-tyramines (o-, m-, and p-hydroxyphenylacetic acids), p-octopamine/p-synephrine (p-hydroxymandelic acid), and dopamine (homovanillic acid and 3,4-dihydroxyphenylacetic acid) were measured in human aqueous humour obtained from patients undergoing elective surgery for cataract removal or for trabeculectomy as a treatment for chronic open-angle glaucoma. There were no clear differences in the pattern of metabolism of neurotransmitters between the two groups. An unexpected finding was that the o-tyramine metabolite, o-hydroxyphenylacetic acid, was present in aqueous humour.
