Etufugh Chukwuemeka N, Phillips Tania J
Section on Dermatopharmacology, Department of Dermatology-Boston University School of Medicine, Boston, MA 02118, USA.
Clin Dermatol. 2007 Jan-Feb;25(1):121-30. doi: 10.1016/j.clindermatol.2006.09.004.
Chronic venous ulceration is a common and important medical problem, which causes significant morbidity. Venous ulcers are expensive to treat, have substantial economic effects in terms of days of work lost, and adversely impact patient's quality of life. History and clinical findings are helpful in making the diagnosis of venous ulceration, but additional diagnostic testing is helpful in confirming the diagnosis and excluding arterial disease. The objectives of venous ulcer management include healing of the ulcer, prevention of recurrence, and improvement of edema. Compression is the cornerstone of venous ulcer therapy. Adjunctive modalities such as biologic skin substitutes, dressings, debridement, surgical intervention, and drugs may also facilitate the healing process.
慢性静脉溃疡是一个常见且重要的医学问题,会导致严重的发病率。静脉溃疡治疗费用高昂,在误工天数方面具有重大经济影响,并且对患者的生活质量产生不利影响。病史和临床检查结果有助于诊断静脉溃疡,但额外的诊断测试有助于确诊并排除动脉疾病。静脉溃疡管理的目标包括溃疡愈合、预防复发以及减轻水肿。加压治疗是静脉溃疡治疗的基石。生物皮肤替代物、敷料、清创术、手术干预和药物等辅助治疗方法也可能促进愈合过程。