Herschthal Jordana, Kirsner Robert S
Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Surg Technol Int. 2008;17:77-83.
Chronic venous ulceration is a common and important medical problem that causes significant morbidity. Venous ulcers are expensive to treat, have substantial economic effects in terms of days of work lost, and adversely impact the patient's quality of life. Relying on evidence allows for a rationale of clinical decision making. The objectives of venous ulcer management include the healing of the ulcer, prevention of recurrence, and improvement of edema. Compression is the cornerstone of venous ulcer therapy. Adjunctive modalities such as surgery, growth factors, grafting, biologic skin substitutes, dressings, and oral medication have differing levels of evidence supporting their use, and may also facilitate the healing process.
慢性静脉溃疡是一个常见且重要的医学问题，会导致严重的发病率。静脉溃疡治疗费用高昂，在误工天数方面具有重大经济影响，并对患者的生活质量产生不利影响。依靠证据有助于进行合理的临床决策。静脉溃疡管理的目标包括溃疡愈合、预防复发和减轻水肿。加压治疗是静脉溃疡治疗的基石。诸如手术、生长因子、移植、生物皮肤替代品、敷料和口服药物等辅助治疗方式，其使用所依据的证据水平各不相同，也可能有助于愈合过程。
