Wright Gail E, Nowak Cheryl A, Goldberg Caren S, Ohye Richard G, Bove Edward L, Rocchini Albert P
Division of Pediatric Cardiology, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Ann Thorac Surg. 2005 Oct;80(4):1453-9. doi: 10.1016/j.athoracsur.2005.04.002.
The surgical repair of aortic coarctation in infants has evolved over time. This study evaluates our current approach utilizing extended end-to-end anastomosis without prosthetic material to enlarge all areas of aortic arch hypoplasia.
The Michigan Congenital Heart Center database was reviewed for infants who underwent repair of isolated aortic coarctation from January 1, 1990, to January 1, 2000.
Eighty-three infants underwent surgical repair of isolated coarctation during this decade. Median age at repair was 21 days (range, 2 to 365). Repair was performed through thoracotomy in 72 patients. Because of severe transverse arch hypoplasia, the remaining 11 infants underwent median sternotomy with circulatory arrest. There were 2 deaths: 1 due to pulmonary hypertension in a patient with alveolar capillary dysplasia and 1 late death due to pneumonia in a patient with noncardiac anomalies. Neither patient had residual coarctation. Technique-related complications of bronchial compression, chylothorax, and vocal cord paralysis were noted in 4 patients. Follow-up data were available for 66 patients (80%) with mean follow-up duration of 4.5 years (SD +/- 3.1). Reintervention was required in 4 patients (6%). One underwent reoperation after 1 month, and 3 underwent balloon angioplasty within 7 months of initial repair. The remaining 61 patients are asymptomatic, on no antihypertensive medications, and have aortic arch gradients less than 15 mm Hg. One developed subaortic stenosis necessitating resection.
Tailored surgical repair for aortic coarctation has a low rate (6%) of residual and recurrent coarctation even when performed in infants. Mortality and morbidity are low.
婴儿主动脉缩窄的手术修复方法随时间不断发展。本研究评估了我们目前采用无人工材料的延长端端吻合术来扩大主动脉弓发育不全所有区域的方法。
回顾密歇根先天性心脏病中心数据库中1990年1月1日至2000年1月1日期间接受单纯主动脉缩窄修复术的婴儿。
在这十年间,83例婴儿接受了单纯主动脉缩窄的手术修复。修复时的中位年龄为21天(范围2至365天)。72例患者通过开胸手术进行修复。由于严重的横弓发育不全,其余11例婴儿接受了在循环停止下的正中胸骨切开术。有2例死亡:1例因肺泡毛细血管发育异常患者的肺动脉高压死亡,1例因非心脏畸形患者的肺炎导致的晚期死亡。两例患者均无残余缩窄。4例患者出现了与技术相关的并发症,包括支气管受压、乳糜胸和声带麻痹。66例患者(80%)有随访数据,平均随访时间为4.5年(标准差±3.1)。4例患者(6%)需要再次干预。1例在1个月后接受了再次手术,3例在初次修复后7个月内接受了球囊血管成形术。其余61例患者无症状,未服用抗高血压药物,主动脉弓压差小于15 mmHg。1例发生主动脉瓣下狭窄,需要进行切除。
即使在婴儿中进行,针对主动脉缩窄的个体化手术修复残余和复发性缩窄的发生率较低(6%)。死亡率和发病率较低。