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主动脉缩窄——外科手术和经导管治疗的现状

Coarctation of the aorta - the current state of surgical and transcatheter therapies.

作者信息

Vergales Jeffrey E, Gangemi James J, Rhueban Karen S, Lim D Scott

机构信息

Children’s Hospital Heart Center, Department of Pediatrics, University of Virginia, USA.

出版信息

Curr Cardiol Rev. 2013 Aug;9(3):211-9. doi: 10.2174/1573403x113099990032.

Abstract

Aortic coarctation represents a distinct anatomic obstruction as blood moves from the ascending to the descending aorta and can present in a range of ages from infancy to adulthood. While it is often an isolated and discrete narrowing, it can also be seen in the more extreme scenario of severe arch hypoplasia as seen in the hypoplastic left heart syndrome or in conjunction with numerous other congenital heart defects. Since the first description of an anatomic surgical repair over sixty years ago, an evolution of both surgical and transcatheter therapies has occurred allowing clinicians to manage and treat this disease with excellent results and low morbidity and mortality. This review focuses on the current state of both transcatheter and surgical therapies, paying special attention to recent data on long-term follow-up of both approaches. Further, current thoughts will be explored about future therapeutic options that attempt to improve upon historical long-term outcomes.

摘要

主动脉缩窄是一种独特的解剖学梗阻,当血液从升主动脉流向降主动脉时出现,可在从婴儿期到成年期的一系列年龄段中出现。虽然它通常是孤立且离散的狭窄,但在诸如左心发育不全综合征等严重主动脉弓发育不良的更极端情况下也可见到,或者与许多其他先天性心脏缺陷同时存在。自从六十多年前首次描述解剖学手术修复以来,手术和经导管治疗都有了发展,使临床医生能够管理和治疗这种疾病,取得了良好的效果,且发病率和死亡率较低。本综述重点关注经导管和手术治疗的现状,特别关注这两种方法长期随访的最新数据。此外,还将探讨当前关于未来治疗选择的想法,这些选择试图改善既往的长期治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbdd/3780346/7165782695c7/CCR-9-211_F1.jpg

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