Gregersen H, Kwiatek M A, Schwizer W, Tutuian R
Center for Visceral Biomechanics and Pain, Aalborg Hospital and University, Aalborg, Denmark.
Neurogastroenterol Motil. 2007 Jan;19(1 Suppl):47-61. doi: 10.1111/j.1365-2982.2006.00874.x.
Upper gastrointestinal (GI) symptoms occur frequently in the general population, making them among the most common indications responsible for patients consulting the healthcare system. Consequently, understanding and characterization of the upper GI symptoms is important for the diagnosis and assessment of organ dysfunction. In practice, assessment of clinical symptoms is difficult and it is still to a large extent unclear how sensitivity, volume and tone contribute to visceral perception in the upper GI tract. The goal of advanced research in upper GI symptoms is to obtain a better understanding of the mechanisms involved in transduction, transmission, and perception under normal and pathophysiological conditions. An important step towards this goal is understanding the information provided by and the inherent limitations of the currently available measuring techniques. This article focuses on the sensory testing of the oesophagus, and methods and concepts used to assess the relation between gastric volumes or tone and upper GI symptoms. It also summarizes the contributions of these techniques towards identifying the components responsible for the generation of upper GI symptoms.
上消化道（GI）症状在普通人群中频繁出现，使其成为患者咨询医疗系统的最常见指征之一。因此，对上消化道症状的理解和特征描述对于器官功能障碍的诊断和评估至关重要。在实践中，临床症状的评估很困难，而且在很大程度上仍不清楚敏感性、容量和张力如何影响上消化道的内脏感觉。上消化道症状的前沿研究目标是更好地理解正常和病理生理条件下转导、传递和感知所涉及的机制。朝着这个目标迈出的重要一步是了解现有测量技术所提供的信息及其固有的局限性。本文重点关注食管的感觉测试，以及用于评估胃容量或张力与上消化道症状之间关系的方法和概念。它还总结了这些技术在识别导致上消化道症状产生的因素方面所做的贡献。
