Stefánsson E, Machemer R, de Juan E, McCuen B W, Peterson J
Department of Ophthalmology, University of Iceland, Reykjavik.
Am J Ophthalmol. 1992 Jan 15;113(1):36-8. doi: 10.1016/s0002-9394(14)75750-2.
The oxygen tension in the preretinal vitreous cavity was measured in human patients undergoing vitreous operations for proliferative diabetic retinopathy. The oxygen tension was significantly higher (P = .004) over areas of retina that had been treated with panretinal photocoagulation than it was over untreated areas in the same retina. This confirmed previous results in animals that showed that panretinal photocoagulation increases the inner retinal oxygen tension. We concluded that panretinal photocoagulation improves the oxygen supply to the inner retina and thereby minimizes the influence of retinal ischemia in diabetic retinopathy.
在接受增殖性糖尿病视网膜病变玻璃体手术的人类患者中,测量了视网膜前玻璃体腔中的氧张力。与同一视网膜中未接受治疗的区域相比,接受全视网膜光凝治疗的视网膜区域的氧张力显著更高(P = 0.004)。这证实了先前在动物实验中的结果,即全视网膜光凝会增加视网膜内层的氧张力。我们得出结论,全视网膜光凝可改善视网膜内层的氧供应,从而将糖尿病视网膜病变中视网膜缺血的影响降至最低。