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视网膜功能成像仪的临床应用:简要综述。

Clinical applications of the retinal functional imager: A brief review.

机构信息

Department of Vitreo-Retina, Narayana Nethralaya Eye Institute, Rajajinagar, Bengaluru, Karnataka, India.

出版信息

Indian J Ophthalmol. 2019 Oct;67(10):1531-1535. doi: 10.4103/ijo.IJO_1824_18.

DOI:10.4103/ijo.IJO_1824_18
PMID:31546475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6786236/
Abstract

The advances in treating blinding conditions often depends on the development of new techniques that allows early detection, treatment, and follow-up of the disease. Functional changes often precede structural changes in many retinal disorders. Therefore, detecting these changes helps in early diagnosis and management, with the intention of preventing permanent morbidity. The Retinal Functional Imager (RFI) is a non-invasive imaging system that allows us to assess the various functional parameters of the retina. The RFI quantitatively measures the retinal blood-flow velocity, oxygen saturation, metabolic demand and generates a non-invasive capillary perfusion map that provides details similar to a fluorescein angiography. All of these parameters correlate with the health of the retina, and are known to get deranged in retinal disease. This article is a brief review of published literature on the clinical utility of the RFI.

摘要

治疗致盲性疾病的进展往往取决于新技术的发展,这些新技术可以实现疾病的早期发现、治疗和随访。在许多视网膜疾病中,功能变化往往先于结构变化。因此,检测这些变化有助于早期诊断和管理,目的是预防永久性发病。视网膜功能成像仪(RFI)是一种非侵入性成像系统,它可以让我们评估视网膜的各种功能参数。RFI 定量测量视网膜血流速度、氧饱和度、代谢需求,并生成一个非侵入性的毛细血管灌注图,提供类似于荧光素血管造影的详细信息。所有这些参数都与视网膜的健康状况相关,并且已知在视网膜疾病中会出现异常。本文是对 RFI 临床应用的已发表文献的简要回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/31fd5d7a51a1/IJO-67-1531-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/2e52c31420c1/IJO-67-1531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/f69317f270f7/IJO-67-1531-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/ca5859c994ec/IJO-67-1531-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/f7d9709a69ba/IJO-67-1531-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/1fe0f02b06d2/IJO-67-1531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/671d6c3ced03/IJO-67-1531-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/147d4e57b51c/IJO-67-1531-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/31fd5d7a51a1/IJO-67-1531-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/2e52c31420c1/IJO-67-1531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/f69317f270f7/IJO-67-1531-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/ca5859c994ec/IJO-67-1531-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/f7d9709a69ba/IJO-67-1531-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/1fe0f02b06d2/IJO-67-1531-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/671d6c3ced03/IJO-67-1531-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/147d4e57b51c/IJO-67-1531-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96f/6786236/31fd5d7a51a1/IJO-67-1531-g008.jpg

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本文引用的文献

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Characterization of retinal microvasculature in acute non-arteritic anterior ischemic optic neuropathy using the retinal functional imager: a prospective case series.使用视网膜功能成像仪对急性非动脉炎性前部缺血性视神经病变的视网膜微血管特征进行研究:一项前瞻性病例系列研究。
Eye Vis (Lond). 2019 Jan 6;6:3. doi: 10.1186/s40662-018-0126-x. eCollection 2019.
2
The retinal function imager and clinical applications.视网膜功能成像仪及其临床应用。
Eye Vis (Lond). 2018 Aug 12;5:20. doi: 10.1186/s40662-018-0114-1. eCollection 2018.
3
A Mini Review of Clinical and Research Applications of the Retinal Function Imager.
视网膜功能成像仪的临床与研究应用综述
Curr Eye Res. 2018 Mar;43(3):273-288. doi: 10.1080/02713683.2017.1414853. Epub 2018 Jan 8.
4
Utility of noninvasive imaging modalities in a retina practice.非侵入性成像模态在视网膜诊疗中的应用
Indian J Ophthalmol. 2016 Dec;64(12):940-943. doi: 10.4103/0301-4738.198850.
5
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6
The effect of intravitreal bevacizumab (Avastin) injection on retinal blood flow velocity in patients with choroidal neovascularization.玻璃体内注射贝伐单抗(阿瓦斯汀)对脉络膜新生血管患者视网膜血流速度的影响。
Eur J Ophthalmol. 2012 May-Jun;22(3):423-30. doi: 10.5301/ejo.5000074.
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