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犬颌面部区域的颌面部横纹肌肉瘤

Maxillofacial rhabdomyosarcoma in the canine maxillofacial area.

作者信息

Nakaichi Munekazu, Itamoto Kazuhito, Hasegawa Keiko, Morimoto Masahiro, Hayashi Toshiharu, Une Satoshi, Taura Yasuho, Tanaka Katsuaki

机构信息

Department of Veterinary Surgery, Faculty of Agriculture, Yamaguchi University, Japan.

出版信息

J Vet Med Sci. 2007 Jan;69(1):65-7. doi: 10.1292/jvms.69.65.

DOI:10.1292/jvms.69.65
PMID:17283403
Abstract

Three dogs had a diagnosis of maxillofacial rhabdomyosarcoma. These dogs were treated with surgery and/or radiotherapy, and had poor clinical responses. The tumor tissues in all three cases were observed around the upper premolar teeth with ulcerative lesions and CT examinations in each case revealed extensive bony involvement into the maxilla. Two cases were subjected to surgical excision of the tissues, followed by an external radiation therapy. The other case was only treated with palliative radiation. Outcomes of the treatment of all the cases were quite poor because of the invasive and refractory nature of the tumor cells, leading to the local recurrence and lung metastasis early in the clinical course. All dogs died within two months of the first admission.

摘要

三只狗被诊断为颌面部横纹肌肉瘤。这些狗接受了手术和/或放疗,但临床反应不佳。所有三例病例的肿瘤组织均在上颌前磨牙周围观察到,伴有溃疡性病变,且每例病例的CT检查均显示上颌骨有广泛的骨质受累。两例进行了组织的手术切除,随后进行了外照射放疗。另一例仅接受了姑息性放疗。由于肿瘤细胞具有侵袭性和难治性,所有病例的治疗结果都很差,导致在临床过程早期出现局部复发和肺转移。所有狗在首次入院后两个月内死亡。

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Identification of tumor-initiating cells derived from two canine rhabdomyosarcoma cell lines.源自两种犬横纹肌肉瘤细胞系的肿瘤起始细胞的鉴定。
J Vet Med Sci. 2017 Jul 7;79(7):1155-1162. doi: 10.1292/jvms.16-0412. Epub 2017 May 21.