Binah O, Rosen M R
Department of Physiology and Biophysics, Faculty of Medicine, The Technion, Haifa, Israel.
Circulation. 1992 Jan;85(1 Suppl):I25-31.
Ventricular arrhythmias may result from abnormalities of impulse initiation and/or impulse propagation. The former include automatic arrhythmias, which may occur at high (normal) levels of membrane potential or at low (abnormal) levels of membrane potential. They also include triggered activity, which may result from early (occurring before complete repolarization) or delayed (occurring after complete repolarization) afterdepolarizations. Arrhythmias resulting from abnormal impulse propagation may be reentrant, determined in part by anatomic or functional conduction block, or the result of reflection. The factors determining various arrhythmogenic mechanisms are discussed.
室性心律失常可能由冲动起始异常和/或冲动传导异常引起。前者包括自律性心律失常，其可发生于膜电位的高（正常）水平或低（异常）水平。还包括触发活动，其可能由早期（在完全复极化之前发生）或延迟（在完全复极化之后发生）后除极引起。由异常冲动传导导致的心律失常可能是折返性的，部分由解剖或功能性传导阻滞决定，或是反射的结果。本文讨论了决定各种致心律失常机制的因素。
