房间阻滞：栓塞性卒中的一个新的危险因素？
Interatrial block: a novel risk factor for embolic stroke?
作者信息
Ariyarajah Vignendra, Puri Puneet, Apiyasawat Sirin, Spodick David H
机构信息
Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), Veterans' Affairs Boston Healthcare System, Boston, MA 02130, USA.
出版信息
Ann Noninvasive Electrocardiol. 2007 Jan;12(1):15-20. doi: 10.1111/j.1542-474X.2007.00133.x.
Abstract
BACKGROUND
Interatrial block (IAB; P wave > or = 110 ms) is highly prevalent and is strongly associated with atrial tachyarrhythmias and left atrial dysfunction, making it a potential embolic risk.
METHODS AND RESULTS
Among 293 neurological admissions over 2 years, 85 patients were diagnosed with embolic strokes and 208 with nonembolic strokes. Patients were then matched for stroke risk factors and evaluated for IAB. Eighty-eight percent of probable embolic stroke patients showed sinus rhythm, demonstrating a 61% IAB prevalence. Only hypertension (P < 0.001; r = 0.3) and IAB (P < 0.006; r = 0.2) were significant and directly correlated.
CONCLUSION
IAB could indeed be a novel risk for embolic strokes and further investigation is warranted.
摘要
背景
房间隔阻滞（IAB；P波≥110毫秒）极为常见，且与房性快速心律失常及左心房功能障碍密切相关，使其成为潜在的栓塞风险因素。
方法与结果
在两年间的293例神经科住院患者中，85例被诊断为栓塞性卒中，208例为非栓塞性卒中。随后根据卒中风险因素对患者进行匹配，并评估IAB情况。88%的可能栓塞性卒中患者表现为窦性心律，IAB患病率为61%。仅有高血压（P<0.001；r = 0.3）和IAB（P<0.006；r = 0.2）具有显著相关性且为直接相关。
结论
IAB确实可能是栓塞性卒中的一个新风险因素，有必要进一步研究。
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