Iomini Pablo A, Martínez-Sellés Manuel, Elosua Roberto, Bayés-de-Luna Antoni, Baranchuk Adrián
Facultad de Medicina, Universidad de Buenos Aires (UBA), UDH Hospital Dr. Prof. Alejandro Posadas. Buenos Aires, Argentina. Universidad de Buenos Aires Facultad de Medicina Universidad de Buenos Aires (UBA) Buenos Aires Argentina.
Centro de Investigación en Red de Enfermedades Cardiovasculares (CIBERCV). España Centro de Investigación Red de Enfermedades Cardiovasculares (CIBERCV) España.
Arch Peru Cardiol Cir Cardiovasc. 2021 Mar 31;2(1):27-39. doi: 10.47487/apcyccv.v2i1.126. eCollection 2021 Jan-Mar.
Bayés's syndrome is a clinical entity based on the association between advanced interatrial block and the development of supraventricular tachyarrhythmia, being atrial fibrillation (AF) the most frequent. This association was discovered by Prof. Antoni Bayés de Luna in the '80s. Further studies by other groups found a strong relationship between Bayés's syndrome and thromboembolic phenomena, being stroke the most serious. Moreover, patients with this syndrome have an increased incidence of cognitive impairment and dementia. This observation triggered the question about whether the use of anticoagulation therapy prior to the documentation of AF could prevent A-IAB associated thromboembolic events. There are ongoing studies in different phases of development aiming to compare the efficacy of anticoagulation in patients with A-IAB with no prior documentation of AF. The outcomes of these studies will allow determining the efficacy of this early therapeutic intervention, and help deciding the role of anticoagulation in patients with A-IAB and no demonstrated AF.
贝耶斯综合征是一种基于晚期心房阻滞与室上性快速心律失常发生之间关联的临床实体,其中房颤(AF)最为常见。这种关联是由安东尼·贝耶斯·德·卢纳教授在20世纪80年代发现的。其他研究小组的进一步研究发现,贝耶斯综合征与血栓栓塞现象之间存在密切关系,其中中风最为严重。此外,该综合征患者认知障碍和痴呆的发生率增加。这一观察引发了一个问题,即在记录房颤之前使用抗凝治疗是否可以预防与A-IAB相关的血栓栓塞事件。目前有处于不同研发阶段的研究,旨在比较在无房颤既往记录的A-IAB患者中抗凝治疗的疗效。这些研究的结果将有助于确定这种早期治疗干预的疗效,并有助于确定抗凝在无明确房颤的A-IAB患者中的作用。