中国四川省南部注射吸毒人群中艾滋病毒的持续传播。
Continued spread of HIV among injecting drug users in southern Sichuan Province, China.
作者信息
Yin Lu, Qin Guangming, Qian Han-Zhu, Zhu Yu, Hu Wei, Zhang Li, Chen Kanglin, Wang Yunxia, Liu Shizhu, Zhou Feng, Xing Hui, Ruan Yuhua, Wang Ning, Shao Yiming
机构信息
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Xuanwu District, Beijing 100050, China.
出版信息
Harm Reduct J. 2007 Feb 8;4:6. doi: 10.1186/1477-7517-4-6.
OBJECTIVE
To estimate HIV prevalence among injecting drug users (IDUs) in a drug trafficking city in southwest Sichuan Province, China.
METHODS
A total of 314 IDUs was invited to participate in the cross-sectional survey in 2004 through community outreach recruitment and peer referrals. Blood sample was taken for HIV antibody testing and a structured questionnaire was administered to collect information on socio-demographics, drug using and sexual behaviors.
RESULTS
HIV prevalence among IDUs was 17.8% (56/314), about one half higher than that in previous survey in 2002 (11.3%, 43/379). Yi and other minority ethnicity (Odds ratio [OR], 3.1; 95% confidence interval [CI], 1.7-5.8; P < 0.001), and total times of sharing injecting equipment 1-9 times versus none, OR, 2.7; 95% CI 1.2-6.2; P = 0.02; and > or = 10 times versus none, OR, 7.5; 95% CI, 3.2-17.7; P < 0.001) were independent risk factors for HIV infection.
CONCLUSION
IDUs with high prevalence rates of HIV and equipment sharing behavior in the drug trafficking city may serve a source for further spread of HIV to other areas in China. The increasing trend of HIV epidemic among IDUs underscores the urgency of scaling up interventions.
目的
评估中国四川省西南部一个毒品交易城市注射吸毒者中的艾滋病毒感染率。
方法
2004年，通过社区宣传招募和同伴推荐，共邀请了314名注射吸毒者参与横断面调查。采集血样进行艾滋病毒抗体检测，并发放结构化问卷以收集社会人口统计学、吸毒和性行为方面的信息。
结果
注射吸毒者中的艾滋病毒感染率为17.8%（56/314），比2002年之前的调查结果（11.3%，43/379）高出约一半。彝族及其他少数民族（优势比[OR]，3.1；95%置信区间[CI]，1.7 - 5.8；P < 0.001），以及共用注射器具总次数为1 - 9次与从未共用相比，OR，2.7；95% CI 1.2 - 6.2；P = 0.02；共用次数≥10次与从未共用相比，OR，7.5；95% CI，3.2 - 17.7；P < 0.001）是艾滋病毒感染的独立危险因素。
结论
在这个毒品交易城市中，艾滋病毒感染率高且存在共用器具行为的注射吸毒者可能成为艾滋病毒在中国其他地区进一步传播的源头。注射吸毒者中艾滋病毒流行趋势的上升凸显了扩大干预措施的紧迫性。
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