Panda S, Chatterjee A, Bhattacharjee S, Ray B, Saha M K, Bhattacharya S K
National Institute of Cholera and Enteric Diseases, Calcutta, India.
Int J STD AIDS. 1998 Apr;9(4):214-8. doi: 10.1258/0956462981922061.
Injecting drug users (IDUs) were recruited from the streets of Calcutta to obtain a baseline biological and behavioural data on risk practices. One-fifth of them (mostly using buprenorphine) tested positive for hepatitis B surface antigen (HBsAg); 4% were reactive to serologic test for syphilis (VDRL: Venereal Disease Research Laboratory). Condom use was insignificant while 74% reported sex with female sex workers and 15% of male IDUs also reported having sex with men. Although, sharing of injecting equipment ('works') was perceived as dangerous by the IDUs, majority of them (90/103) reportedly shared it; cleaning of works before sharing was a concern for intravenous but not for intramuscular drug injecting. Half of the IDUs reported suffering ever from abscess; a proportion (12%) of which had had superadded attack of maggots in it. They were also found to be infected with HIV (1%, 95% CI 0.028-5.97%) at a low prevalence that prompted subsequent launching of needle syringe exchange programme, establishment of cleaning norms before sharing of works, cleaning of injecting site on the body and condom promotion.
从加尔各答街头招募注射吸毒者,以获取关于风险行为的基线生物学和行为数据。其中五分之一(大多使用丁丙诺啡)的人乙肝表面抗原(HBsAg)检测呈阳性;4%的人梅毒血清学检测(性病研究实验室玻片试验:VDRL)呈反应性。使用避孕套的情况不显著,74%的人报告与女性性工作者发生过性行为,15%的男性注射吸毒者还报告与男性发生过性行为。尽管注射吸毒者认为共用注射器具(“工具”)很危险,但据报告大多数人(90/103)会共用;共用前对工具进行清洁是静脉注射吸毒者而非肌肉注射吸毒者所关心的问题。一半的注射吸毒者报告曾患过脓肿;其中一部分(12%)还出现过蛆虫滋生的情况。他们还被发现感染艾滋病毒的比例较低(1%,95%可信区间0.028 - 5.97%),这促使随后开展针头注射器交换项目、制定共用工具前的清洁规范、清洁身体上的注射部位以及推广使用避孕套。