Pasquini Massimo, Biondi Massimo
Department of Psychiatry and Psychological Medicine, University La Sapienza of Rome, Italy.
Clin Pract Epidemiol Ment Health. 2007 Feb 8;3:2. doi: 10.1186/1745-0179-3-2.
Cancer patients experience several stressors and emotional upheavals. Fear of death, interruption of life plans, changes in body image and self-esteem, changes in social role and lifestyle are all important issues to be faced. Moreover, Depressive Disorders may impact the course of the disease and compliance. The cost and prevalence, the impairment caused, and the diagnostic and therapeutic uncertainty surrounding depressive symptoms among cancer patients make these conditions a priority for research. In this article we discuss recent data, focusing on detection of Depressive Disorders, biological correlates, treatments and unmet needs of depressed cancer patients.
癌症患者会经历多种压力源和情绪动荡。对死亡的恐惧、生活计划的中断、身体形象和自尊的变化、社会角色和生活方式的改变都是需要面对的重要问题。此外，抑郁症可能会影响疾病进程和治疗依从性。癌症患者中抑郁症状的成本、患病率、所造成的损害以及诊断和治疗的不确定性，使得这些情况成为研究的重点。在本文中，我们讨论了近期的数据，重点关注抑郁症的检测、生物学关联、治疗方法以及癌症抑郁症患者未满足的需求。
