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[心室辅助装置作为移植的桥梁]

[Ventricular assist devices as a bridge to transplantation].

作者信息

Reyes Guillermo, Fernández-Yáñez Juan, Rodríguez-Abella Hugo, Palomo Jesús, Pinto Angel, Duarte Juan

机构信息

Servicio de Cirugía Cardiovascular, Hospital Universitario La Princesa, Madrid, Spain.

出版信息

Rev Esp Cardiol. 2007 Jan;60(1):72-5.

PMID:17288959
Abstract

We carried out an analysis of the results obtained in patients (n=23) who received a ventricular assist device before heart transplantation between 1988 and 2005. Their mean age was 52.5 (8.4) years. Reasons for inclusion in the transplantation waiting list were postcardiotomy referral (n=10), myocardial infarction (n=5), primary graft dysfunction (n=7), and dilated cardiomyopathy (n=1). Different types of ventricular assist device were used: the Abiomed 5000 (n=13), the Biomed Comunidad de Madrid (n=9), and the BioMedicus (n=1). The mean transplantation waiting time was 3.0 (2.4) days. In-hospital complications were neurological (n=7), infectious (n=12), renal (n=3), hemorrhagic (n=3), and respiratory (n=2). In-hospital mortality was 39.1% (n=9). Kaplan-Meier analysis gave a 1-year survival rate of 55.2% and a 5-year survival rate of 32.2%. In patients who were discharged home, the 1-year survival rate was 92.3%. Careful patient selection is essential for obtaining good results.

摘要

我们对1988年至2005年间在心脏移植前接受心室辅助装置的患者(n = 23)所获得的结果进行了分析。他们的平均年龄为52.5(8.4)岁。列入移植等候名单的原因有心内直视手术后转诊(n = 10)、心肌梗死(n = 5)、原发性移植物功能障碍(n = 7)和扩张型心肌病(n = 1)。使用了不同类型的心室辅助装置:Abiomed 5000(n = 13)、马德里自治区生物医学装置(n = 9)和百特生物医学公司的装置(n = 1)。平均移植等候时间为3.0(2.4)天。住院并发症包括神经方面(n = 7)、感染方面(n = 12)、肾脏方面(n = 3)、出血方面(n = 3)和呼吸方面(n = 2)。住院死亡率为39.1%(n = 9)。Kaplan-Meier分析得出1年生存率为55.2%,5年生存率为32.2%。出院回家的患者1年生存率为92.3%。仔细的患者选择对于获得良好结果至关重要。

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1
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Rev Esp Cardiol. 2007 Jan;60(1):72-5.
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