Pae W E
Department of Surgery, Pennsylvania State University College of Medicine, Hershey 17033.
Ann Thorac Surg. 1993 Jan;55(1):295-8. doi: 10.1016/0003-4975(93)90540-x.
Data submitted voluntarily to the combined registry for the past 6 years on the use of ventricular assist devices for postcardiotomy cardiogenic shock in 965 patients and for circulatory support in conjunction with cardiac transplantation in 544 patients were analyzed. Of those patients whose ventricular function was expected to recover, approximately 45% were weaned from circulatory support and 25% were discharged from the hospital. Weaning status and hospital discharge were not different regardless of the type of original operative procedure or the pump design used. In the potential cardiac transplant group, 69% ultimately underwent transplantation and 66% were discharged from the hospital. The demographics (age and sex) of this group parallel those of patients undergoing isolated cardiac transplantation, and the 1- and 2-year survival estimates for patients requiring only univentricular support were equivalent to those of patients having isolated orthotopic cardiac transplantation. Ventricular assist devices are able to provide reasonable and safe circulatory support in both the postcardiotomy cardiogenic shock and the bridge-to-transplantation applications.
对过去6年自愿提交至联合登记处的数据进行了分析,这些数据涉及965例患者在心脏切开术后心源性休克中使用心室辅助装置的情况,以及544例患者在心脏移植联合循环支持中的情况。在那些预期心室功能会恢复的患者中,约45%成功脱离循环支持,25%出院。无论最初的手术方式或所使用的泵的设计如何,脱离支持状态和出院情况并无差异。在潜在心脏移植组中,69%最终接受了移植,66%出院。该组的人口统计学特征(年龄和性别)与接受单纯心脏移植的患者相似,仅需要单心室支持的患者的1年和2年生存估计与接受单纯原位心脏移植的患者相当。心室辅助装置能够在心脏切开术后心源性休克和过渡到移植应用中提供合理且安全的循环支持。