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创伤性颈动脉瘤夹层

Traumatic cervical artery dissection.

作者信息

Nedeltchev K, Baumgartner R

机构信息

Institute of Diagnostic and Interventional Neuroradiology, niversity Hospital of Bern, Bern, Switzerland.

出版信息

Front Neurol Neurosci. 2005;20:54-63. doi: 10.1159/000088149.

Abstract

Traumatic cervical artery dissection (TCAD) is a complication of severe blunt head or neck trauma, the main cause being motor vehicle accidents. TCAD are increasingly recognized, and incidences of up to 0.86% for internal carotid and 0.53% for traumatic vertebral artery dissections (TVAD) among blunt trauma victims are reported. Diagnostic evaluation for TCAD is mandatory in the presence of (1) hemorrhage of potential arterial origin originating from the nose, ears, mouth, or a wound; (2) expanding cervical hematoma; (3) cervical bruit in a patient >50 years of age; (4) evidence of acute infarct at brain imaging; (5) unexplained central or lateralizing neurological deficit or transient ischemic attack, or (6) Horner syndrome, neck or head pain. In addition, a number of centers screen asymptomatic patients with blunt trauma for TCAD. Catheter angiography is the standard of reference for diagnosis of TCAD. Color duplex ultrasound, computed tomographic, and magnetic resonance angiography are noninvasive screening alternatives, but each method has its diagnostic limitations compared to catheter angiography. Anticoagulants and antiplatelet drugs may prevent ischemic stroke, but bleeding from traumatized tissues may offset the benefits of antithrombotic treatment. Endovascular therapy of dissected vessels, thrombarterectomy, direct suture of intimal tears, and extracranial-intracranial bypass should be considered in exceptional cases. Neurological outcome is probably worse in TCAD compared to spontaneous CAD, although it is unclear whether this is due to dissection-induced ischemic stroke or associated traumatic lesions.

摘要

创伤性颈动脉瘤夹层(TCAD)是严重钝性头部或颈部创伤的一种并发症,主要病因是机动车事故。TCAD越来越受到重视,据报道,钝性创伤受害者中颈内动脉夹层的发生率高达0.86%,创伤性椎动脉夹层(TVAD)的发生率为0.53%。在出现以下情况时,必须对TCAD进行诊断评估:(1)源于鼻、耳、口或伤口的潜在动脉源性出血;(2)颈部血肿扩大;(3)年龄>50岁患者出现颈部杂音;(4)脑成像显示急性梗死的证据;(5)无法解释的中枢性或定位性神经功能缺损或短暂性脑缺血发作,或(6)霍纳综合征、颈部或头部疼痛。此外,一些中心会对无症状的钝性创伤患者进行TCAD筛查。导管血管造影是诊断TCAD的参考标准。彩色双功超声、计算机断层扫描和磁共振血管造影是非侵入性筛查方法,但与导管血管造影相比,每种方法都有其诊断局限性。抗凝剂和抗血小板药物可能预防缺血性中风,但创伤组织出血可能抵消抗栓治疗的益处。在特殊情况下,应考虑对夹层血管进行血管内治疗、血栓切除术、内膜撕裂直接缝合以及颅外-颅内搭桥术。与自发性颈动脉瘤夹层相比,TCAD患者的神经功能预后可能更差,尽管尚不清楚这是由于夹层引起的缺血性中风还是相关的创伤性病变所致。

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